Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease
about
The toxicity of amyloid β oligomersDown-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's diseaseMitochondrial oxidative stress in aging and healthspanPlasmodium falciparum merozoite surface protein 3: oligomerization, self-assembly, and heme complex formationCytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's diseaseInteractions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.Current and future uses of neuroimaging for cognitively impaired patients.Hemoglobin binding to A beta and HBG2 SNP association suggest a role in Alzheimer's diseaseCombined measurement of PEDF, haptoglobin and tau in cerebrospinal fluid improves the diagnostic discrimination between alzheimer's disease and other dementias.A mitochondrial etiology of Alzheimer and Parkinson diseasePotential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseasesApoHRP-based assay to measure intracellular regulatory heme.Protective effects of curcumin in APPswe transfected SH-SY5Y cellsG-quadruplex structures formed by expanded hexanucleotide repeat RNA and DNA from the neurodegenerative disease-linked C9orf72 gene efficiently sequester and activate heme.Curcumin inhibits appoptosin-induced apoptosis via upregulating heme oxygenase-1 expression in SH-SY5Y cellsMutations in cytochrome c oxidase subunit VIa cause neurodegeneration and motor dysfunction in DrosophilaHeme Stabilization of α-Synuclein Oligomers during Amyloid Fibril Formation.Pleiotropic protective effects of phytochemicals in Alzheimer's diseaseOxidative stress and lipid peroxidation are upstream of amyloid pathology.Rescue of PINK1 protein null-specific mitochondrial complex IV deficits by ginsenoside Re activation of nitric oxide signalingThe heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's diseaseInteraction between amyloid-β peptide and heme probed by electrochemistry and atomic force microscopy.Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.Environmental and dietary risk factors in Alzheimer's disease.Haem-assisted dityrosine-cross-linking of fibrinogen under non-thermal plasma exposure: one important mechanism of facilitated blood coagulation.N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration.Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.Development and validation of a chemiluminescent immunodetection assay amenable to high throughput screening of antiviral drugs for Nipah and Hendra virus.Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity.The failure of mitochondria leads to neurodegeneration: Do mitochondria need a jump start?Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease.Intrinsic Peroxidase-like Activity of Ficin.Is Alzheimer's disease amyloidosis the result of a repair mechanism gone astray?The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders.Novel drug targets based on metallobiology of Alzheimer's disease.RNA and DNA complexes with hemin [Fe(III) heme] are efficient peroxidases and peroxygenases: how do they do it and what does it mean?Road to Alzheimer's disease: the pathomechanism underlying.Plant polyphenols in the treatment of age-associated diseases: revealing the pleiotropic effects of icariin by network analysis.Intranasal therapeutic strategies for management of Alzheimer's disease.Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer's disease
P2860
Q24631757-97145104-291A-46C0-88E6-DAC0D6EE0533Q24654632-77A9CDDF-2131-4EDD-B601-D90F270D9154Q27025099-A18FCF29-943C-4AF2-BBA8-B3B6B05BABC9Q27974527-2917F146-B5CE-4A2E-81D9-5EFF7FD4808BQ30443526-DD8B6678-BD8A-4E9E-8102-E5070ECD3C5CQ31050722-893F2F92-480D-48EA-9669-D159E71299E3Q31143267-1A81FCA9-5293-4DED-9621-7FD0E7EC52EEQ33266027-0B63FAD0-5B4D-4B88-AE70-BD44026F1D13Q33821194-E08674AF-5B36-4E79-A543-1FABE18CACF9Q34211127-24B6160A-80AC-42E3-B379-9DA7A5CAC693Q34594807-CB545867-DAE3-44A7-9BAD-3225D4ECCFC3Q35079585-95357F14-B675-4078-A8EB-CA905E4DD98DQ35148858-A371EBCB-D769-41E3-9894-FAEE6584F5BFQ35245567-6084E147-A7AA-4A77-8E8E-F54908AC98B0Q35578526-A6A4AC60-015C-4726-B16B-D20B8B62FCD4Q35846393-1C35BDBC-220E-4C11-8EB6-26C4C227A427Q35920719-1185E42B-20D4-4643-81FB-27AF884F91B5Q36012073-FCB64C13-029C-4BF0-9AF9-426089F0BC92Q36387084-B6B3E173-6342-4456-A247-5AA13DA9E19CQ36492752-27156584-77D0-4001-A69F-DD7BC57EB79FQ36660120-046A8644-FD7B-4ABC-B163-0167728C25C5Q36776386-BFD2863F-EF5C-4591-9EBF-8E67B0FA665EQ36778260-10CCFD82-787C-4DFD-BAF0-E703884BCD02Q36870079-389F197D-CB1D-4F58-AF63-E11339494D06Q36941506-000498C1-1572-40F6-9DAB-D91109797CAFQ37003852-D4094E70-1CF5-430F-A2CA-DFC02C983868Q37101754-EF40A4B8-DB18-40EA-91DD-8C763DE32B0CQ37121907-65235360-1040-4E8F-809E-A5C0F7E89670Q37339912-C4ED2F84-A895-4AB5-8D9D-B12BC325A9D2Q37441183-D1C86B78-E54B-410C-9821-9A1AB216ADF0Q37599515-3E1483FF-32AC-4185-8ACF-38C103A15EE4Q37657762-059587FE-4840-4CF7-9B68-104AF10F341DQ37698598-C94892E4-086E-4A0B-AA60-07E845077BD2Q37725605-D1582F32-3CDB-4534-9488-36759789151DQ37799838-2302B210-AC8E-4189-9FED-1895A2AC659FQ37940577-079380E2-0369-48D7-9756-2BBBF57E4487Q37972068-2CFB11E3-D55B-4FA8-83DF-E7B922A8887FQ38169127-3C6D9948-D8FC-4742-8787-891E8E84FF56Q38176935-2304B4F9-E28A-401D-85AE-573A278A0445Q38197948-6AD5D491-6FE7-4F5F-8F9E-A80984D9D077
P2860
Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@ast
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en-gb
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@nl
type
label
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@ast
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en-gb
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@nl
prefLabel
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@ast
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en-gb
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@nl
P2860
P3181
P356
P1476
Amyloid-beta peptide binds wit ...... ologies of Alzheimer's disease
@en
P2093
Hani Atamna
Kathleen Boyle
P2860
P304
P3181
P356
10.1073/PNAS.0600134103
P407
P577
2006-02-28T00:00:00Z