Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
about
Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrixRoles for the human ATP-dependent Lon protease in mitochondrial DNA maintenanceThermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNADNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substratePossible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality controlAdaptive homeostasisThe Measurement of Reversible Redox Dependent Post-translational Modifications and Their Regulation of Mitochondrial and Skeletal Muscle FunctionMitochondrial and skeletal muscle health with advancing ageMultitasking in the mitochondrion by the ATP-dependent Lon proteaseOxidative stress and pulmonary fibrosisStructure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activityStructures of an ATP-independent Lon-like protease and its complexes with covalent inhibitorsRole of the novel metallopeptidase Mop112 and saccharolysin for the complete degradation of proteins residing in different subcompartments of mitochondria.Structural properties of substrate proteins determine their proteolysis by the mitochondrial AAA+ protease Pim1.Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104pMitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disordersMitochondrial protein quality control: the mechanisms guarding mitochondrial healthMitochondrial quality control in the myocardium: cooperation between protein degradation and mitophagyOxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signalingEvidence that two ATP-dependent (Lon) proteases in Borrelia burgdorferi serve different functionsHypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxinAge-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heartLoss of calpain 10 causes mitochondrial dysfunction during chronic hyperglycemiaReversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusionAge-associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise trainingOxidative stress and neurodegeneration: where are we now?Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells.Microscopic analysis of protein oxidative damage: effect of carbonylation on structure, dynamics, and aggregability of villin headpieceRapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria.Cleavage site selection within a folded substrate by the ATP-dependent lon protease.Rules governing selective protein carbonylation.The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria.Control of mitochondrial integrity in ageing and diseaseThe age- and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in Drosophila melanogasterTetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM.Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.Dopamine quinone modifies and decreases the abundance of the mitochondrial selenoprotein glutathione peroxidase 4.Role of oxidative carbonylation in protein quality control and senescence.Defense against protein carbonylation by DnaK/DnaJ and proteases of the heat shock regulon.Mitochondrial protease AtFtsH4 protects ageing Arabidopsis rosettes against oxidative damage under short-day photoperiod
P2860
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P2860
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@ast
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en-gb
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@nl
type
label
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@ast
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en-gb
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@nl
prefLabel
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@ast
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en-gb
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@nl
P921
P3181
P356
P1433
P1476
Lon protease preferentially de ...... by an ATP-stimulated mechanism
@en
P2093
Kelvin J A Davies
P2888
P304
P3181
P356
10.1038/NCB836
P407
P577
2002-09-01T00:00:00Z
P5875
P6179
1030137194