STIL is required for centriole duplication in human cells
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerRBM14 prevents assembly of centriolar protein complexes and maintains mitotic spindle integrityC2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and humanHuman microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assemblyProduction of Basal Bodies in bulk for dense multicilia formationRegulation of the centrosome cycleCentrosomes, chromosome instability (CIN) and aneuploidyDiseases associated with defective responses to DNA damageSAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism inC. eleganscentriole assemblyCrystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephalyStructural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole ArchitectureThe PLK4-STIL-SAS-6 module at the core of centriole duplicationThe Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesisPotential mechanisms of Zika-linked microcephalyOverexpression of EVI1 interferes with cytokinesis and leads to accumulation of cells with supernumerary centrosomes in G0/1 phase.Loss of centrioles causes chromosomal instability in vertebrate somatic cells.Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancerThe centriole duplication cycle.SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplicationAn integrated overview of spatiotemporal organization and regulation in mitosis in terms of the proteins in the functional supercomplexes.Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole.Cep63 and cep152 cooperate to ensure centriole duplicationThe centrosome and its duplication cycleHomozygous STIL mutation causes holoprosencephaly and microcephaly in two siblings.Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stageSTIL binding to Polo-box 3 of PLK4 regulates centriole duplicationDevelopmental alterations in centrosome integrity contribute to the post-mitotic state of mammalian cardiomyocytesStructured illumination of the interface between centriole and peri-centriolar material.A novel function of the human oncogene Stil: Regulation of PC12 cell toxic susceptibility through the Shh pathway3D-structured illumination microscopy provides novel insight into architecture of human centrosomes.Bld10/Cep135 stabilizes basal bodies to resist cilia-generated forces.WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progressionThe E2F-DP1 Transcription Factor Complex Regulates Centriole Duplication in Caenorhabditis elegans.Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly.CEP120 interacts with CPAP and positively regulates centriole elongationCep295 is a conserved scaffold protein required for generation of a bona fide mother centrioleQuantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging.Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis.Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.Transcription of the SCL/TAL1 interrupting Locus (Stil) is required for cell proliferation in adult Zebrafish Retinas.
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P2860
STIL is required for centriole duplication in human cells
description
2012 nî lūn-bûn
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2012 թուականի Մարտին հրատարակուած գիտական յօդուած
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2012 թվականի մարտին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
STIL is required for centriole duplication in human cells
@ast
STIL is required for centriole duplication in human cells
@en
STIL is required for centriole duplication in human cells
@en-gb
STIL is required for centriole duplication in human cells
@nl
type
label
STIL is required for centriole duplication in human cells
@ast
STIL is required for centriole duplication in human cells
@en
STIL is required for centriole duplication in human cells
@en-gb
STIL is required for centriole duplication in human cells
@nl
prefLabel
STIL is required for centriole duplication in human cells
@ast
STIL is required for centriole duplication in human cells
@en
STIL is required for centriole duplication in human cells
@en-gb
STIL is required for centriole duplication in human cells
@nl
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P3181
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P1476
STIL is required for centriole duplication in human cells
@en
P2093
Ahuvit David
Alexandra Tibelius
Alwin Krämer
Asher Castiel
Felix Bestvater
Fengying Liu
Gleb Konotop
Julia Vulprecht
Marc S Raab
Shai Izraeli
P304
P3181
P356
10.1242/JCS.104109
P407
P577
2012-03-01T00:00:00Z