Tpp1/Acd maintains genomic stability through a complex role in telomere protection
about
Telomere protection by TPP1 is mediated by POT1a and POT1bMultiple facets of TPP1 in telomere maintenanceMultiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.Review paper: origin and molecular pathology of adrenocortical neoplasmsThe E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection.TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in miceAdditive effect of TAp63 deficiency on the adrenocortical dysplasia (acd) phenotype.Adrenocortical stem and progenitor cells: unifying model of two proposed origins.The shelterin complex and hematopoiesis.The Est3 protein associates with yeast telomerase through an OB-fold domain.Genetic p53 deficiency partially rescues the adrenocortical dysplasia phenotype at the expense of increased tumorigenesis.In search of adrenocortical stem and progenitor cellsHematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.Defending the end zone: studying the players involved in protecting chromosome endsIdentification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach.Caudal regression in adrenocortical dysplasia (acd) mice is caused by telomere dysfunction with subsequent p53-dependent apoptosis.
P2860
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P2860
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@ast
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en-gb
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@nl
type
label
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@ast
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en-gb
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@nl
prefLabel
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@ast
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en-gb
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@nl
P2093
P921
P1433
P1476
Tpp1/Acd maintains genomic stability through a complex role in telomere protection
@en
P2093
Brian K Theisen
Catherine E Keegan
David O Ferguson
Gary D Hammer
Tobias Else
P2888
P304
P356
10.1007/S10577-007-1175-5
P407
P50
P577
2007-01-01T00:00:00Z
P6179
1010329009