Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature
about
Ghrelin receptor mutations--too little height and too much hunger.The growth hormone secretagogue receptor: its intracellular signaling and regulationGrowth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target(1,2,3)Ghrelin.Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents.Role of FAT/CD36 in fatty acid sensing, energy, and glucose homeostasis regulation in DIO and DR ratsEvolutionary genetics and implications of small size and twinning in callitrichine primatesThe cellular and molecular bases of leptin and ghrelin resistance in obesity.The role of ghrelin in GH secretion and GH disorders.Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp.Evidence for acyl-ghrelin modulation of growth hormone release in the fed state.Model-projected mechanistic bases for sex differences in growth hormone regulation in humans.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsFamily and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity.Chaperoning G protein-coupled receptors: from cell biology to therapeuticsIntegrating GHS into the Ghrelin System.Genetics of isolated growth hormone deficiency.Enhanced responsiveness of Ghsr Q343X rats to ghrelin results in enhanced adiposity without increased appetite.Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp.Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complexRegulated recovery of pulsatile growth hormone secretion from negative feedback: a preclinical investigation.Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors.Diagnosis of growth hormone deficiency in childhood.Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor SignalingIs Ghrelin Synthesized in the Central Nervous System?Unusual phenotypic features in a patient with a novel splice mutation in the GHRHR gene.Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal womenGonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy menAn intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3.Mechanisms of disease: Mutations of G proteins and G-protein-coupled receptors in endocrine diseases.Ghrelin, the peripheral hunger hormone.Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretionAnxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala.Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal womenGhrelin receptor gene polymorphisms and body size in children and adultsEstrogen elevates the peak overnight production rate of acylated ghrelinAging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and womenObesity vaccines.
P2860
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P2860
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Loss of constitutive activity ...... ptor in familial short stature
@ast
Loss of constitutive activity ...... ptor in familial short stature
@en
Loss of constitutive activity ...... ptor in familial short stature
@en-gb
Loss of constitutive activity ...... ptor in familial short stature
@nl
type
label
Loss of constitutive activity ...... ptor in familial short stature
@ast
Loss of constitutive activity ...... ptor in familial short stature
@en
Loss of constitutive activity ...... ptor in familial short stature
@en-gb
Loss of constitutive activity ...... ptor in familial short stature
@nl
prefLabel
Loss of constitutive activity ...... ptor in familial short stature
@ast
Loss of constitutive activity ...... ptor in familial short stature
@en
Loss of constitutive activity ...... ptor in familial short stature
@en-gb
Loss of constitutive activity ...... ptor in familial short stature
@nl
P2093
P2860
P921
P356
P1476
Loss of constitutive activity ...... ptor in familial short stature
@en
P2093
Abdelkrim Kadiri
Dominique Grouselle
Jacques Epelbaum
Latifa Hilal
Marc de Kerdanet
Marie-Pierre Vie-Luton
Serge Amselem
Sylvie Cabrol
Sylvie Nivot
Séverine Morisset
P2860
P304
P356
10.1172/JCI25303
P407
P577
2006-03-01T00:00:00Z