A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon
about
Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordatesAstrocytes differentially respond to inflammatory autoimmune insults and imbalances of neural activity.Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathwayPhosphorylation and ankyrin-G binding of the C-terminal domain regulate targeting and function of the ammonium transporter RhBGPolarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domainsElectrogenic tuning of the axon initial segmentNeural KCNQ (Kv7) channelsNew molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsTwo variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorderNeurofascin assembles a specialized extracellular matrix at the axon initial segmentThree-dimensional reconstruction of the membrane skeleton at the plasma membrane interface by electron tomographyAxon Initial Segment Cytoskeleton: Architecture, Development, and Role in Neuron PolarityFunctional implications of axon initial segment cytoskeletal disruption in strokeNeuronal polarity: an evolutionary perspectiveTrafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segmentDriving with no brakes: molecular pathophysiology of Kv7 potassium channelsRedistribution of Kv1 and Kv7 enhances neuronal excitability during structural axon initial segment plasticity.Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc.Structural and Functional Plasticity at the Axon Initial SegmentIdentification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-AcyltransferasesInteractions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated discMolecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytesMultiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axonsThe Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ.Coordinated signal integration at the M-type potassium channel upon muscarinic stimulationNodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanismsGenome-wide association and meta-analysis of bipolar disorder in individuals of European ancestryMyelin Loss and Axonal Ion Channel Adaptations Associated with Gray Matter Neuronal HyperexcitabilityActivation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channels through a CRMP-2-mediated pathway.Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity.K(+) channelepsy: progress in the neurobiology of potassium channels and epilepsy.M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission.Function and mechanism of axonal targeting of voltage-sensitive potassium channels.Polarity and intracellular compartmentalization of Drosophila neurons.Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.Localization and targeting of voltage-dependent ion channels in mammalian central neurons.Electron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system.Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons.In vivo assembly of the axon initial segment in motor neuronsIdentifying and Analyzing Novel Epilepsy-Related Genes Using Random Walk with Restart Algorithm.
P2860
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P248
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P2860
A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
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2006年学术文章
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2006年學術文章
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name
A common ankyrin-G-based mecha ...... lly active domains of the axon
@ast
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en-gb
A common ankyrin-G-based mecha ...... lly active domains of the axon
@nl
type
label
A common ankyrin-G-based mecha ...... lly active domains of the axon
@ast
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en-gb
A common ankyrin-G-based mecha ...... lly active domains of the axon
@nl
prefLabel
A common ankyrin-G-based mecha ...... lly active domains of the axon
@ast
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en-gb
A common ankyrin-G-based mecha ...... lly active domains of the axon
@nl
P2093
P921
P3181
P1476
A common ankyrin-G-based mecha ...... lly active domains of the axon
@en
P2093
Edward C Cooper
Jai-Yoon Sul
Julia Lemos
Stephen D Cranstoun
Steven S Scherer
Tingching Kao
Vann Bennett
Zongming Pan
Zsolt Horvath
P304
P3181
P356
10.1523/JNEUROSCI.4314-05.2006
P407
P577
2006-03-08T00:00:00Z