A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell TypesIFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearanceHepatitis C virus protease inhibitor-resistance mutations: our experience and reviewInterferon Lambda 4 Polymorphism Predicts Sustained Viral Response in Hepatitis C Virus Patients Irrespective of Hepatitis C Virus Genotypes, Ethnicity or Treatment Regimen: Results From a Meta-AnalysisNK cell function and receptor diversity in the context of HCV infectionInterferon Response in Hepatitis C Virus (HCV) Infection: Lessons from Cell Culture Systems of HCV InfectionThe yin and yang of hepatitis C: synthesis and decay of hepatitis C virus RNAInterferon-λ: Immune Functions at Barrier Surfaces and BeyondResistance to Rhabdoviridae Infection and Subversion of Antiviral ResponsesImpact of IL28B, ITPA and PNPLA3 genetic variants on therapeutic outcome and progression of hepatitis C virus infectionGenetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine DesignRegulation of hepatic innate immunity by hepatitis C virusInterferon induction by RNA viruses and antagonism by viral pathogensMurine models of hepatitis C: what can we look forward to?Population genetic tools for dissecting innate immunity in humansEmerging concepts in immunity to hepatitis C virus infection.Emerging therapies for the treatment of hepatitis CT cell responses in hepatitis C virus infection: historical overview and goals for future researchMetabolic factors and chronic hepatitis C: a complex interplayPost-transcriptional regulation of interferons and their signaling pathwaysGenetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactionsHepatitis C virus genotype 6: virology, epidemiology, genetic variation and clinical implicationComparison of antiviral activity of lambda-interferons against HIV replication in macrophagesLive Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation MutantTargeted induction of interferon-λ in humanized chimeric mouse liver abrogates hepatotropic virus infectionIFN-λ: A New Inducer of Local Immunity against Cancer and InfectionsClinical Laboratory Testing in the Era of Directly Acting Antiviral Therapies for Hepatitis CInterferons and viruses: an evolutionary arms race of molecular interactionsHepatitis C.Influence of host resistance on viral adaptation: hepatitis C virus as a case studyInterferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burdenType I interferons in infectious diseaseAssociation of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infectionAdvanced molecular surveillance of hepatitis C virusMumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes.Hepatitis E virus persists in the presence of a type III interferon response.Interferon induction and function at the mucosal surface.IL28B polymorphisms and clinical implications for hepatitis C virus infection in UzbekistanThe bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferons
P2860
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P2860
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@ast
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en-gb
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@nl
type
label
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@ast
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en-gb
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@nl
prefLabel
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@ast
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en-gb
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
A variant upstream of IFNL3 (I ...... clearance of hepatitis C virus
@en
P2093
Brian Muchmore
Charles D Howell
David L Thomas
Dianna Hergott
Faruk Sheikh
Harold Dickensheets
Heiyoung Park
Herbert L Bonkovsky
Indu Kohaar
P2860
P2888
P304
P3181
P356
10.1038/NG.2521
P407
P5008
P577
2013-02-01T00:00:00Z
P5875
P6179
1020164243