Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores
about
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stressVanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activityComplex genetic control of susceptibility to malaria: positional cloning of the Char9 locusFLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications.Role of Oxidative Stress in Drug-Induced Kidney InjuryRole of the Vanins-Myeloperoxidase Axis in Colorectal Carcinogenesis.Involvement of MicroRNAs in Probiotics-Induced Reduction of the Cecal Inflammation by Salmonella Typhimurium.The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.Inhibition of transcription factor specificity protein 1 alters the gene expression profile of keratinocytes leading to upregulation of kallikrein-related peptidases and thymic stromal lymphopoietin.Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases.Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrateProtection against cerebral malaria by the low-molecular-weight thiol pantethine.Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank miceEnhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium.Role of iron in the pathogenesis of cysteamine-induced duodenal ulceration in rats.VNN1 overexpression is associated with poor response to preoperative chemoradiotherapy and adverse prognosis in patients with rectal cancers.Genetic and pharmacological inhibition of vanin-1 activity in animal models of type 2 diabetes.Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.A Pharmacogenetic Discovery: Cystamine Protects Against Haloperidol-Induced Toxicity and Ischemic Brain Injury.Analysis of vanin-1 upregulation and lipid accumulation in hepatocytes in response to a high-fat diet and free fatty acids.Peroxisome proliferator-activated receptor alpha target genes.Cysteamine, an Endogenous Aminothiol, and Cystamine, the Disulfide Product of Oxidation, Increase Pseudomonas aeruginosa Sensitivity to Reactive Oxygen and Nitrogen Species and Potentiate Therapeutic Antibiotics against Bacterial Infection.
P2860
Q24300264-7A45A4DA-1E63-44A6-A431-6F627ACC2F6AQ24322799-B1D6A85E-1858-486A-8F29-DC802AD9686FQ24679744-4BF46864-9B63-4EE7-9CDD-8CB9DAB10EEBQ27851415-41595983-4495-42F1-96A0-B00BC8400A12Q28074502-EE8A15A5-6D5E-4FBF-A281-82C008C2815CQ33754814-B405E512-3AC3-46F4-9F6F-5389EE35BBECQ33790258-C6A72DC4-AB12-4BC5-B4E1-85541F2A428EQ34214778-868BB1DD-D35F-4CD8-8D48-FC085F566F88Q35349913-BA464EED-8E44-423D-93D5-8C08C7C3440DQ35675063-9FAED070-2024-410B-B19B-F412BA5D8CFDQ36008839-AF9C2CA4-E240-44B3-ADF2-5B6087659E35Q36446215-428D51A0-93CA-46C7-99E0-29743DC554FBQ36559683-AFE0419C-50D3-4528-BC58-9B28C68D64D4Q36678030-B9C61F16-EF99-49C5-8358-800CD840DB26Q36788489-F26BB29D-F70E-499D-BAC2-F07673815DA9Q37325226-E3FDD4F3-38F2-4C18-A946-FA906ACF4B95Q37393494-AAE02B86-5E87-4C10-B218-38AA27E91868Q38713300-85EEAA77-98B8-4642-BF1C-9C2B7350C6B2Q39534358-F8A8A35D-2A84-4DDA-A406-650952624C27Q41091940-8ED6034B-BCAA-488E-84F4-5CE9C01259A3Q41435617-4007B9D4-6B72-4D2D-B6BE-D3677D238598Q42414964-1942BF44-454D-49C9-8C11-DC55C4803309Q54247894-60DB14B3-5550-41AE-A093-5A743CE83897
P2860
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@ast
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en-gb
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@nl
type
label
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@ast
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en-gb
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@nl
prefLabel
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@ast
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en-gb
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@nl
P2093
P2860
P921
P356
P1476
Vanin-1(-/-) mice show decreas ...... with higher glutathione stores
@en
P2093
Alain Dessein
Bouchra Gharib
Fabrice Malergue
Florent Martin
Franck Galland
Marie-France Penet
Max de Reggi
Philippe Naquet
P2860
P356
10.1172/JCI19557
P407
P577
2004-02-01T00:00:00Z