The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
about
TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKLHelicobacter pylori CagA activates NF-kappaB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitinationDlg5 interacts with the TGF-β receptor and promotes its degradationEmerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer developmentMechanisms of TGFβ-Induced Epithelial-Mesenchymal Transitionp38 MAPK Signaling in Osteoblast DifferentiationReversible Human TGF-β Signal Shifting between Tumor Suppression and Fibro-Carcinogenesis: Implications of Smad Phospho-Isoforms for Hepatic Epithelial-Mesenchymal TransitionsEpithelial-Mesenchymal Transition and Breast CancerTGF-β signaling via TAK1 pathway: role in kidney fibrosisKey role for ubiquitin protein modification in TGFβ signal transductionRegulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsThe age-related changes in cartilage and osteoarthritisMolecular mechanisms of epithelial-mesenchymal transitionThe p38/MK2/Hsp25 pathway is required for BMP-2-induced cell migrationComplexities of TGF-β targeted cancer therapy.Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisTGF-β family signaling in stem cellsInhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cellsc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionGhrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling PathwayTranscriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanismTAK1 is an essential regulator of BMP signalling in cartilageTGF-beta-induced epithelial to mesenchymal transitionNon-Smad pathways in TGF-beta signalingCIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.Non-degradative Ubiquitination of Protein Kinases.Activation of Akt signaling in prostate induces a TGFβ-mediated restraint on cancer progression and metastasis.Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.TGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness.Regulation of Ubiquitin Enzymes in the TGF-β Pathway.Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation.HIV-1 Vpr stimulates NF-κB and AP-1 signaling by activating TAK1.Mechanisms of the epithelial-mesenchymal transition by TGF-betaThe regulation of TGF-β/SMAD signaling by protein deubiquitination.A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritisTRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2.TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathway
P2860
Q21092160-D9DDA69A-577F-4F90-8CBA-C391A39CD200Q24324189-2A91E9C4-8AC8-4665-98C2-1D1480640E23Q24339424-73B80428-0142-4611-B47F-1BF7A218E233Q24622802-065FB1C1-24B3-48B8-ACAA-8F64CB90BD0FQ26745545-E719331E-4B6F-4A7A-99B4-89F0DF7F488CQ26747239-4EDB296A-8E46-4BD6-A078-57A749A8451DQ26771696-50213E06-89D7-406A-8415-4B1A4DC2FF1CQ26773055-215EA19C-36D4-40FC-926B-DDF5B1CB8EEFQ26824337-3702EDEE-5525-4B9D-91C4-DF97B3FED6EAQ26824916-0C34C2A9-204E-44F0-9DBE-EE80468A6536Q26827667-E7050E3A-D218-4513-842B-F4F004499E5AQ26863325-39E3B01E-7D78-47AE-8B07-8C0732B67B28Q27013743-056CDDFC-F470-4DB3-9E25-1D20EC535FE2Q27437628-7F37B76A-D8E7-4194-BD8A-6D1B1573241AQ27693607-9D18DFA8-CCAC-4630-B784-2471D9375044Q28081170-D039182C-B9AB-4D85-95A5-DAA6C061457DQ28083107-3AF5E8D4-C9B9-470E-A385-EEF6A701464DQ28274611-4073B300-9346-480F-AB05-2B53E245BDD1Q28481277-B904E297-E7FB-4055-89A4-DFECDD09E651Q28504995-FF1B9D6E-8DA3-4FDF-A404-314C5C1BF4EAQ28551406-DCEBA777-5196-4E0E-9B08-70F3EC22E92DQ28585338-2E4F9799-E88B-4B9C-BF14-B17ABEE8D144Q28586793-963C23A7-FD52-4259-A116-36A101B50D8EQ29619820-217E29A9-40E7-4DD7-AC7A-F79D5BE9841FQ29620040-883B5A0C-8869-49C4-B82A-791CF848EC85Q30009137-E4C2861D-1CDE-47AD-91D9-270008073DEDQ30388842-9CFB8F3C-99FC-4C48-8D02-B8865094903FQ30408632-FB2F871D-2738-4D16-81CC-C9EE6D801A68Q31813050-C3099409-C79C-4EB4-B4A8-EDE61593C039Q33553472-386B1C5C-9F47-494E-8320-7FB3CF721EA3Q33592822-D0BCD203-6D20-41CA-A98E-785736B15F1DQ33624967-51F74002-DF80-4EA9-BC05-A2BF36A5A9D8Q33648347-94903268-4E6C-46FF-BD78-ABF5FDF38D72Q33756614-3D4605FA-1034-4D04-94DD-22C92F57EA3CQ33804105-7ED5A6C4-DCAB-4F16-953F-D9AC66371238Q33857612-F3E280DA-5C2D-4063-8C66-D289C044C17BQ33873604-96B4E541-4D59-42D5-8591-0472952C4AADQ33931833-A87023C2-487F-4A37-8796-924B92B977B3Q34028544-4BB9FF95-2DB5-401C-AE06-01A6A5854163Q34043345-636BDB76-A0DD-4C48-B402-DE48D47F215B
P2860
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@ast
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en-gb
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@nl
type
label
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@ast
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en-gb
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@nl
prefLabel
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@ast
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en-gb
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@nl
P2093
P3181
P356
P1433
P1476
The type I TGF-beta receptor e ...... ptor kinase-independent manner
@en
P2093
Alessandro Sorrentino
Anders Marcusson
Carl-Henrik Heldin
Noopur Thakur
Norbert Schuster
Shouting Zhang
Susanne Grimsby
Verena von Bulow
P2888
P304
P3181
P356
10.1038/NCB1780
P407
P577
2008-10-01T00:00:00Z
P5875
P6179
1023242636