Clustered base substitutions in CTP synthetase conferring drug resistance in Chinese hamster ovary cells
about
Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotransferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targetsMechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complexEffect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae.Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are laxCommon regulatory control of CTP synthase enzyme activity and filament formationThe Interplay between Myc and CTP Synthase in Drosophila.CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae.Metabolic regulation via enzyme filamentationGenetic factors influencing cytarabine therapy.A single point mutation in CTP synthetase of Chlamydia trachomatis confers resistance to cyclopentenyl cytosine.Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy.Thr-431 and Arg-433 are part of a conserved sequence motif of the glutamine amidotransferase domain of CTP synthases and are involved in GTP activation of the Lactococcus lactis enzyme.Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.Engineered cytidine triphosphate synthetase with reduced product inhibition.Exploring the Potent Inhibition of CTP Synthase by Gemcitabine-5'-Triphosphate.
P2860
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P2860
Clustered base substitutions in CTP synthetase conferring drug resistance in Chinese hamster ovary cells
description
1993 nî lūn-bûn
@nan
1993 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Clustered base substitutions i ...... in Chinese hamster ovary cells
@ast
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en-gb
Clustered base substitutions i ...... in Chinese hamster ovary cells
@nl
type
label
Clustered base substitutions i ...... in Chinese hamster ovary cells
@ast
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en-gb
Clustered base substitutions i ...... in Chinese hamster ovary cells
@nl
prefLabel
Clustered base substitutions i ...... in Chinese hamster ovary cells
@ast
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en-gb
Clustered base substitutions i ...... in Chinese hamster ovary cells
@nl
P2093
P3181
P356
P1433
P1476
Clustered base substitutions i ...... in Chinese hamster ovary cells
@en
P2093
P2888
P304
P3181
P356
10.1038/NG0493-317
P407
P577
1993-04-01T00:00:00Z
P5875
P6179
1034242186