Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity
about
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysisMode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activityTrinucleotide repeats: a structural perspectiveThe challenge of producing ubiquitinated proteins for structural studiesCharacterization of the conformational fluctuations in the Josephin domain of ataxin-3.Allosteric regulation of deubiquitylase activity through ubiquitination.Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5).Enhanced molecular mobility of ordinarily structured regions drives polyglutamine diseaseDistinct X-chromosome SNVs from some sporadic AD samplesAtaxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 modelsThe 2.2-Angstrom resolution crystal structure of the carboxy-terminal region of ataxin-3.JosD1, a membrane-targeted deubiquitinating enzyme, is activated by ubiquitination and regulates membrane dynamics, cell motility, and endocytosisEnzymatic production of mono-ubiquitinated proteins for structural studies: The example of the Josephin domain of ataxin-3.The de-ubiquitinating enzyme ataxin-3 does not modulate disease progression in a knock-in mouse model of Huntington disease.Regulation of proteolysis by human deubiquitinating enzymes.Mechanisms for regulating deubiquitinating enzymes.The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells.MJD and OTU deubiquitinating enzymes in Schistosoma mansoni.The evolution and functional diversification of the deubiquitinating enzyme superfamily.Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding.
P2860
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P2860
Crystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@ast
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en-gb
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@nl
type
label
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@ast
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en-gb
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@nl
altLabel
Crystal Structure of a Josephi ...... IN-3 DEUBIQUITINATING ACTIVITY
@en
prefLabel
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@ast
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en-gb
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@nl
P2093
P2860
P921
P356
P1476
Crystal structure of a Josephi ...... in-3 deubiquitinating activity
@en
P2093
Kimberly C Grasty
Lisa Hernandez-Cuebas
Patrick J Loll
Stephen D Weeks
P2860
P304
P356
10.1074/JBC.M110.177360
P407
P577
2011-02-11T00:00:00Z