Menin, the product of the MEN1 gene, is a nuclear protein
about
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signalingThe tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivationMenin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chainDirect binding of DNA by tumor suppressor meninMenin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activationMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDThe 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor geneGlobal gene expression in neuroendocrine tumors from patients with the MEN1 syndromeFamilial syndromes associated with neuroendocrine tumoursCrystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsMultiple endocrine neoplasia type 1Burin from Mauritius: a novel MEN1 mutationMenin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23Growth hormone-secreting tumors: genetic aspects and data from animal modelsMultiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)MEN1 tumor-suppressor protein localizes to telomeres during meiosisMenin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4cTumor suppressor menin regulates expression of insulin-like growth factor binding protein 2Reduction of menin expression enhances cell proliferation and is tumorigenic in intestinal epithelial cellsMenin induces apoptosis in murine embryonic fibroblastsConditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissuesA mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumorsImpact of a novel 14 bp MEN1 deletion in a patient with hyperparathyroidism and gastrinoma.Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells.Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation.The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.Menin mediates Tat-induced neuronal apoptosis in brain frontal cortex of SIV-infected macaques and in Tat-treated cells.Identification of somatic mutations in parathyroid tumors using whole-exome sequencingAn oncogenic role for the multiple endocrine neoplasia type 1 gene in prostate cancer.Sporadic endocrine tumours and their relationship to the hereditary endocrine neoplasia syndromes.FBP1 Is an Interacting Partner of Menin.Menin is a regulator of the stress response in Drosophila melanogasterMultiple endocrine neoplasia.Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disordersMenin immunoreactivity in secretory granules of human pancreatic islet cellsBilateral adrenocortical carcinoma in a patient with multiple endocrine neoplasia type 1 (MEN1) and a novel mutation in the MEN1 gene.The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.Genetic analysis of a patient with coexisting acromegaly, thyroid papillary carcinoma and subcutaneous fibroma.
P2860
Q21145267-2E8F5B09-937E-48D5-A041-BDF5AE4B6F09Q24290996-6B9855FE-2370-4D31-AF9B-821945D069CFQ24291618-59FDF9EB-4715-4CA6-A351-ED677A2A6B7AQ24293576-A00CEF7D-FA51-45A6-975C-E2F5DF574D7CQ24295255-F359D751-8A7A-4DA4-A0BD-8BE8B196D7F7Q24301985-BE5D9725-F058-4F1F-9D26-6979530BEAC2Q24306677-E827B558-0EDB-411D-AA82-36500E70DA26Q24316533-BC8892FD-9EA1-43BC-8A67-8E847029C927Q24338184-532005ED-FF57-4A82-A8AD-79A54DEDB768Q24806559-625601DA-8B53-48F2-8B14-F7A76C028F9FQ26777791-14B270E6-1065-4228-9907-A28D9756D916Q27670797-44138FED-D8FA-4C02-AFB5-D4A624269CCDQ28088746-9BB1C6BB-5B51-49BC-B402-8FB20CA5E63DQ28214101-A41B6FDC-EC4F-4B7D-AE4A-871F5AFCDA9CQ28216208-E1910365-E4EA-4F2F-9A0C-FA56F92F98C2Q28268972-04E0C396-6EA1-4AD0-96DA-C33D86728927Q28296266-0496CDC2-07CB-40B4-BAA2-22BCAAE35149Q28505590-0580B258-B59C-4BD1-BB00-88453E13C8F1Q28506197-DC3F6CC0-1F0E-4AFF-89C2-52E0C87390C1Q28506714-DAC8EA5F-6F77-4686-881C-F6A81123A5F2Q28579115-E9F8B915-B3EA-44B9-B69B-718035E5BE4AQ28589504-B8AC960B-B4E7-454B-AAE8-A2FB69773383Q28589655-20E3E7A9-3EB0-4F93-88BC-936988184846Q28592210-6C6ABD14-8BD9-45C1-B955-9929DD6915F0Q30376908-646B8E46-895C-460A-896E-F836002A2A4CQ30438923-841C6025-EDBB-4F79-AB6C-D456A5D67ED0Q33278294-D7392C8D-207C-42AC-8911-AB044E9B14A1Q33358543-9F8488DA-B0DF-44F8-B86C-A8B8438A69B0Q33566813-BD52F452-03F5-4B07-9696-E0044D792143Q33569943-97B5B973-B573-4CBA-AC2D-02C81FA3DCFBQ33747848-ECF2ECEC-E963-489B-BD26-6EBD747324ADQ33940347-F2DCE722-D6D3-4304-AED3-7AB8A263A728Q34009803-31A92EC0-F798-42AA-8068-34A5F95B7AB7Q34124168-CE0C0C8E-76EE-4189-ADC6-4B09A13BC0D7Q34151612-BCAD7AA8-46EF-4BD9-9AD4-F43A8EDADBEBQ34386474-7C584E95-59BC-44BE-B97F-CDD7750A89A8Q34514134-283C1DFA-3548-40AC-BF33-E3C9F91F02AEQ34576778-C69A9934-B092-4FE8-ABD6-D0A749D0EE12Q34789134-6B85C299-7DDC-429B-9C6B-3CD0D923E8D5Q35042041-82522772-6305-4B65-9A52-ACC6ED736B2A
P2860
Menin, the product of the MEN1 gene, is a nuclear protein
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Menin, the product of the MEN1 gene, is a nuclear protein
@ast
Menin, the product of the MEN1 gene, is a nuclear protein
@en
Menin, the product of the MEN1 gene, is a nuclear protein
@en-gb
Menin, the product of the MEN1 gene, is a nuclear protein
@nl
type
label
Menin, the product of the MEN1 gene, is a nuclear protein
@ast
Menin, the product of the MEN1 gene, is a nuclear protein
@en
Menin, the product of the MEN1 gene, is a nuclear protein
@en-gb
Menin, the product of the MEN1 gene, is a nuclear protein
@nl
prefLabel
Menin, the product of the MEN1 gene, is a nuclear protein
@ast
Menin, the product of the MEN1 gene, is a nuclear protein
@en
Menin, the product of the MEN1 gene, is a nuclear protein
@en-gb
Menin, the product of the MEN1 gene, is a nuclear protein
@nl
P2093
P2860
P3181
P356
P1476
Menin, the product of the MEN1 gene, is a nuclear protein
@en
P2093
A M Spiegel
P K Goldsmith
S C Chandrasekharappa
P2860
P304
P3181
P356
10.1073/PNAS.95.4.1630
P407
P577
1998-02-17T00:00:00Z