A human STX cDNA confers polysialic acid expression in mammalian cells
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Expression cloning and functional characterization of human cDNA for ganglioside GM3 synthaseMolecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipidsMolecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IVDifferential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha 2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia IIIIdentification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase familyMolecular cloning and expression of GDP-D-mannose-4,6-dehydratase, a key enzyme for fucose metabolism defective in Lec13 cellsHuman STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PSTSialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regenerationStructure and Mutagenesis of Neural Cell Adhesion Molecule Domains: EVIDENCE FOR FLEXIBILITY IN THE PLACEMENT OF POLYSIALIC ACID ATTACHMENT SITESNCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migrationEngineering of complex protein sialylation in plants.Retinoic acid-induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells.Glycobiology of neuroblastoma: impact on tumor behavior, prognosis, and therapeutic strategies.Polysialyltransferase-1 autopolysialylation is not requisite for polysialylation of neural cell adhesion molecule.Unique disulfide bond structures found in ST8Sia IV polysialyltransferase are required for its activity.The polysialyltransferase ST8Sia II/STX: posttranslational processing and role of autopolysialylation in the polysialylation of neural cell adhesion molecule.ST8Sia II and ST8Sia IV polysialyltransferases exhibit marked differences in utilizing various acceptors containing oligosialic acid and short polysialic acid. The basis for cooperative polysialylation by two enzymes.Polysialic acid and mucin type o-glycans on the neural cell adhesion molecule differentially regulate myoblast fusion.Sequences from the first fibronectin type III repeat of the neural cell adhesion molecule allow O-glycan polysialylation of an adhesion molecule chimera.Characterization of mouse ST8Sia II (STX) as a neural cell adhesion molecule-specific polysialic acid synthase. Requirement of core alpha1,6-linked fucose and a polypeptide chain for polysialylation.Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX.In vivo autopolysialylation and localization of the polysialyltransferases PST and STX.Sequences at the interface of the fifth immunoglobulin domain and first fibronectin type III repeat of the neural cell adhesion molecule are critical for its polysialylationSequences prior to conserved catalytic motifs of polysialyltransferase ST8Sia IV are required for substrate recognition.Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells.The polysialyltransferases interact with sequences in two domains of the neural cell adhesion molecule to allow its polysialylationExperimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo.Identification of sequences in the polysialyltransferases ST8Sia II and ST8Sia IV that are required for the protein-specific polysialylation of the neural cell adhesion molecule, NCAM.Polysialic acid: versatile modification of NCAM, SynCAM 1 and neuropilin-2.Polysialic acid: biosynthesis, novel functions and applications.Mutation of the sialyltransferase S-sialylmotif alters the kinetics of the donor and acceptor substrates.Sialic acids in cancer biology and immunity.Characterization of the major core structures of the alpha2-->8-linked polysialic acid-containing glycan chains present in neural cell adhesion molecule in embryonic chick brains.Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST-1).Autocatalytic polysialylation of polysialyltransferase-1.A human polysialyltransferase directs in vitro synthesis of polysialic acid.Genomic structure and promoter activity of the mouse polysialic acid synthase gene (mST8Sia II). Brain-specific expression from a TATA-less GC-rich sequence.Polysialylation promotes neural cell adhesion molecule-mediated cell migration in a fibroblast growth factor receptor-dependent manner, but independent of adhesion capability.Differential biosynthesis of polysialic or disialic acid Structure by ST8Sia II and ST8Sia IV.
P2860
Q22008027-7C7D19B3-03C3-434E-B50A-D8A6431510A6Q22009402-00280270-08D2-455A-AFE2-0D713FB48C5CQ22009412-12EA7E1D-87C3-4BB9-BCEC-7AA29088270BQ22253906-B03F3E20-AA7B-4F8B-8A1C-956FE19B4F1EQ24290427-9AF2C0B3-7093-4F8A-ACB5-50DEFF3C7499Q24320145-39AC81E4-02EB-40EB-9B3E-A881B16D85BAQ24324255-675CCFAA-1E2D-4CA7-8F4D-D746E047F9ABQ26995291-87FD4D98-3FF7-42D0-BFFC-E1C9BD459B08Q27662651-9C8463DC-D3A4-45E2-9288-2E7ABFC0AF89Q28071519-53877230-AB7B-4D9B-944A-AB899B1BB148Q28535224-C2CD65DE-03B4-4D31-897C-4E7730360761Q30313981-3514C386-4D0C-43CE-86E4-3488D4EA29CAQ31659432-C2F3B59A-DA24-41FC-BCB7-A9FA8C77CF86Q33659849-A06DB7BB-93FB-445C-B792-F0F923CF3C0BQ33888933-02946A14-7D67-4DF0-B112-D4D8D01A861EQ33940590-5BEFEEFE-207C-479F-BACB-47AB97EE6098Q34105202-AA5F4908-B038-4B9B-AC14-EDB70EFED907Q34140948-E95A373E-7110-4C69-825B-734CC5D95F8EQ34246992-D19F87C6-84ED-4F37-9E1D-62B096C19F0CQ34251447-2D2B5412-D19D-462C-861F-36AF1BAD6FBAQ34388496-4A3D1BDE-4F45-473C-979D-B33CF3DC8CDFQ34475448-2B854E2E-4F05-43A8-80DF-4B1D33754AFBQ34483408-DAEF34B4-8D4D-4067-A4F8-009C1D77938EQ34575750-CD33D5E9-EFD8-4775-97E7-1E83EDB6627DQ35838994-24DD111C-B30C-49DF-95A1-81AC7CEF2C2BQ36370665-91D93C94-7AAC-4380-85AB-667F79ADD113Q36666264-447BC311-FE6E-48D2-9C94-8F1FC77AC7C8Q36994551-2F28C947-155E-4EE1-932E-E99A85262B48Q37257286-BCB97B12-3EC8-44ED-AE8F-90BBD869EF32Q38077108-8D72ED9D-FB74-45E6-84D2-02EE596FFDF8Q38265379-146744B7-E0F6-42D1-8E5F-7FB537005518Q38337475-D2BE721E-754D-4D1E-A9CC-AA1D00484089Q38620799-DA38A31A-15E4-4A1A-A215-8631C303A0C5Q40916479-E6DEE3C7-6995-4394-B776-0975B032793DQ40987114-1A80A931-348E-483D-9224-445947933174Q41079025-2BD1B3A0-E3E0-48BF-8825-5EE0CF37D752Q41237275-CB0F9524-B304-48F7-A643-19589CF600F0Q42806854-D58AEFD6-7381-4A3D-A819-A2085121C651Q42813877-37A11C04-35DA-4502-8971-7BBB288B691BQ43559751-650B4D09-A132-4941-BEC2-EBAB41792C98
P2860
A human STX cDNA confers polysialic acid expression in mammalian cells
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
A human STX cDNA confers polysialic acid expression in mammalian cells
@ast
A human STX cDNA confers polysialic acid expression in mammalian cells
@en
A human STX cDNA confers polysialic acid expression in mammalian cells
@en-gb
A human STX cDNA confers polysialic acid expression in mammalian cells
@nl
type
label
A human STX cDNA confers polysialic acid expression in mammalian cells
@ast
A human STX cDNA confers polysialic acid expression in mammalian cells
@en
A human STX cDNA confers polysialic acid expression in mammalian cells
@en-gb
A human STX cDNA confers polysialic acid expression in mammalian cells
@nl
prefLabel
A human STX cDNA confers polysialic acid expression in mammalian cells
@ast
A human STX cDNA confers polysialic acid expression in mammalian cells
@en
A human STX cDNA confers polysialic acid expression in mammalian cells
@en-gb
A human STX cDNA confers polysialic acid expression in mammalian cells
@nl
P2093
P2860
P356
P1476
A human STX cDNA confers polysialic acid expression in mammalian cells
@en
P2093
E P Scheidegger
L R Sternberg
P2860
P304
P356
10.1074/JBC.270.39.22685
P407
P577
1995-09-29T00:00:00Z