PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity
about
Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle ProgressionHistone demethylases in chromatin biology and beyondMinireview: Recent advances in extranuclear steroid receptor actionsMolecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST ComplexLSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 DemethylationKDM1 class flavin-dependent protein lysine demethylasesProline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage responseRegulation of rDNA transcription by proto-oncogene PELP1PELP1 overexpression in the mouse mammary gland results in the development of hyperplasia and carcinomaSignificance of PELP1 in ER-negative breast cancer metastasisLAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesisNovel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cellsCentral role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancerMinireview: Deciphering the Cellular Functions of PELP1Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancerLSD1 inhibition: a therapeutic strategy in cancer?PELP1 oncogenic functions involve CARM1 regulationCyclin-dependent kinase-mediated phosphorylation plays a critical role in the oncogenic functions of PELP1PELP1: a review of PELP1 interactions, signaling, and biologySignificance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancerPELP1 oncogenic functions involve alternative splicing via PRMT6Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasisReaders of histone methylarginine marks.The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memoryA core chromatin remodeling factor instructs global chromatin signaling through multivalent reading of nucleosome codes.Proline-, glutamic acid-, and leucine-rich protein 1 mediates estrogen rapid signaling and neuroprotection in the brainEstrogens Correlate with PELP1 Expression in ER Positive Breast CancerIdentification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.PELP1: Structure, biological function and clinical significance.Epigenetic regulation of estrogen signaling in breast cancerLysine-Specific Demethylase 1 (LSD1) Inhibitor S2101 Induces Autophagy via the AKT/mTOR Pathway in SKOV3 Ovarian Cancer Cells.Histone demethylases in chromatin cross-talks.Epigenetics of estrogen receptor signaling: role in hormonal cancer progression and therapy.Acidic domains differentially read histone H3 lysine 4 methylation status and are widely present in chromatin-associated proteins.Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway.Inhibitors of LSD1 as a potential therapy for acute myeloid leukemia.TCPs: privileged scaffolds for identifying potent LSD1 inhibitors for cancer therapy.ERRα induces H3K9 demethylation by LSD1 to promote cell invasion.CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells
P2860
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P2860
PELP1 is a reader of histone H3 methylation that facilitates oestrogen receptor-alpha target gene activation by regulating lysine demethylase 1 specificity
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@ast
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en-gb
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@nl
type
label
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@ast
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en-gb
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@nl
prefLabel
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@ast
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en-gb
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@nl
P2093
P2860
P356
P1433
P1476
PELP1 is a reader of histone H ...... sine demethylase 1 specificity
@en
P2093
Binoj C Nair
Darrell W Brann
Dimple Chakravarty
Eric Metzger
Rajeshwar R Tekmal
Ratna K Vadlamudi
Roland Schüle
Sujit S Nair
Valerie Cortez
P2860
P304
P356
10.1038/EMBOR.2010.62
P407
P577
2010-06-01T00:00:00Z