Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site
about
CLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrilsBrain-specific deletion of extracellular signal-regulated kinase 2 mitogen-activated protein kinase leads to aberrant cortical collagen deposition.COL25A1 triggers and promotes Alzheimer's disease-like pathology in vivo.Interruptions in the collagen repeating tripeptide pattern can promote supramolecular association.A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brainA peptide study of the relationship between the collagen triple-helix and amyloidWhole-Genome Sequencing of a Healthy Aging Cohort.Abeta aggregation and possible implications in Alzheimer's disease pathogenesisIFN-beta pharmacogenomics in multiple sclerosis.
P2860
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P2860
Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Characterization of the Alzhei ...... loid beta-peptide-binding site
@ast
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en-gb
Characterization of the Alzhei ...... loid beta-peptide-binding site
@nl
type
label
Characterization of the Alzhei ...... loid beta-peptide-binding site
@ast
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en-gb
Characterization of the Alzhei ...... loid beta-peptide-binding site
@nl
prefLabel
Characterization of the Alzhei ...... loid beta-peptide-binding site
@ast
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en-gb
Characterization of the Alzhei ...... loid beta-peptide-binding site
@nl
P2093
P2860
P921
P356
P1476
Characterization of the Alzhei ...... loid beta-peptide-binding site
@en
P2093
Anna Möller
Hiroyoshi Kakuyama
Jan Näslund
Lars O Tjernberg
Linda Söderberg
P2860
P304
P356
10.1074/JBC.M403628200
P407
P577
2005-01-14T00:00:00Z