Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs
about
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placentaMutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.Adenosine and hypoxia-inducible factor signaling in intestinal injury and recoveryGlial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity?Nucleoside transporter proteins of Saccharomyces cerevisiae. Demonstration of a transporter (FUI1) with high uridine selectivity in plasma membranes and a transporter (FUN26) with broad nucleoside selectivity in intracellular membranes.Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparumLocalization of the Plasmodium falciparum PfNT1 nucleoside transporter to the parasite plasma membraneCloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocationCloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell lineMolecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brainIdentification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2Cladribine induces apoptosis in human leukaemia cells by caspase-dependent and -independent pathways acting on mitochondriaNucleoside transporter subtype expression: effects on potency of adenosine kinase inhibitorsMolecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridineDifferential transport of cytosine-containing nucleosides by recombinant human concentrative nucleoside transporter protein hCNT1Inhibiting the growth of pancreatic adenocarcinoma in vitro and in vivo through targeted treatment with designer gold nanotherapeuticsThe Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem CellsImmunocytochemical demonstration of the equilibrative nucleoside transporter rENT1 in rat sinoatrial nodeControl of glutamatergic neurotransmission in the rat spinal dorsal horn by the nucleoside transporter ENT1Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cellsChronic hypoxia enhances adenosine release in rat PC12 cells by altering adenosine metabolism and membrane transportIdentification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2Equilibrative nucleoside transporters-A review.Genomic analysis of nucleoside transporters in Diptera and functional characterization of DmENT2, a Drosophila equilibrative nucleoside transporter.The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression.Adenosine and hemodialysis in humans.Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC).Identification of the ENT1 antagonists dipyridamole and dilazep as amplifiers of oncolytic herpes simplex virus-1 replicationThe type 1 equilibrative nucleoside transporter regulates anxiety-like behavior in miceXenobiotic, bile acid, and cholesterol transporters: function and regulation.Families of transmembrane sugar transport proteins.Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms.In vivo labeling of fission yeast DNA with thymidine and thymidine analogs.Identification and characterization of a novel monoamine transporter in the human brain.Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture.Implication of the purinergic system in alcohol use disorders.
P2860
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P2860
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@ast
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en-gb
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@nl
type
label
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@ast
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en-gb
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@nl
prefLabel
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@ast
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en-gb
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@nl
P2093
P921
P356
P1433
P1476
Cloning of a human nucleoside ...... ine and chemotherapeutic drugs
@en
P2093
C E Boumah
M Griffiths
M Sundaram
N Beaumont
S A Baldwin
P2860
P2888
P356
10.1038/NM0197-89
P407
P577
1997-01-01T00:00:00Z
P6179
1030383867