Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
about
Novel Structural Approaches to Study GPCR RegulationHigh vascular tone of mouse femoral arteries in vivo is determined by sympathetic nerve activity via α1A- and α1D-adrenoceptor subtypesAlpha(1D)-adrenergic receptor insensitivity is associated with alterations in its expression and distribution in cultured vascular myocytesEpistasis analysis for quantitative traits by functional regression model.Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.The alpha-syntrophin PH and PDZ domains scaffold acetylcholine receptors, utrophin, and neuronal nitric oxide synthase at the neuromuscular junction.α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries.Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.Differences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targetingAdiponectin receptor 1 C-terminus interacts with PDZ-domain proteins such as syntrophins.Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules.Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.Dynamic mass redistribution reveals diverging importance of PDZ-ligands for G protein-coupled receptor pharmacodynamicsLXR Agonism Upregulates the Macrophage ABCA1/Syntrophin Protein Complex That Can Bind ApoA-I and Stabilized ABCA1 Protein, but Complex Loss Does Not Inhibit Lipid Efflux.Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene clusterWhen worlds collide: IP(3) receptors and the ERAD pathway.LQTS-associated mutation A257G in α1-syntrophin interacts with the intragenic variant P74L to modify its biophysical phenotype.Substrate-specific mediators of ER associated degradation (ERAD).SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.Fine-tuning of GPCR activity by receptor-interacting proteinsSarcoplasmic reticulum function in smooth muscle.Functional signaling biases in G protein-coupled receptors: Game Theory and receptor dynamics.Central Arterial Function Measured by Non-invasive Pulse Wave Analysis is Abnormal in Patients with Duchenne Muscular Dystrophy.Label-Free Dynamic Mass Redistribution Reveals Low-Density, Prosurvival α1B-Adrenergic Receptors in Human SW480 Colon Carcinoma Cells.GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactionsCarboxyl terminus-truncated α1D-adrenoceptors inhibit the ERK pathway.Disease-causing mutation in GPR54 reveals the importance of the second intracellular loop for class A G-protein-coupled receptor function.Syntrophin isoforms play specific functional roles in the α1D-adrenergic receptor/DAPC signalosome.Endogenous N-terminal Domain Cleavage Modulates α1D-Adrenergic Receptor Pharmacodynamics.Evaluation of the specificity of four commercially available antibodies to alpha-syntrophin.The molecular cross talk of the dystrophin-glycoprotein complex.
P2860
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P2860
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@ast
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en-gb
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@nl
type
label
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@ast
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en-gb
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@nl
prefLabel
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@ast
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en-gb
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@nl
P2093
P2860
P356
P1476
Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome
@en
P2093
Angie L Hertz
Chris Hague
David B Feller
Jennifer L Wacker
John S Lyssand
Marvin E Adams
Mia C DeFino
Xiao-bo Tang
P2860
P304
P356
10.1074/JBC.M801860200
P407
P577
2008-07-04T00:00:00Z