Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
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Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymesAutoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activityA third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domainsThe large form of ADAR 1 is responsible for enhanced hepatitis delta virus RNA editing in interferon-alpha-stimulated host cellsPurification of human double-stranded RNA-specific editase 1 (hRED1) involved in editing of brain glutamate receptor B pre-mRNARNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleusEditing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminasesFunctionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminaseEditing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infectionIncreased RNA editing and inhibition of hepatitis delta virus replication by high-level expression of ADAR1 and ADAR2.Inhibition of hepatitis delta virus RNA editing by short inhibitory RNA-mediated knockdown of ADAR1 but not ADAR2 expression.Substrate recognition by ADAR1 and ADAR2Antiviral actions of interferonsThe role of binding domains for dsRNA and Z-DNA in the in vivo editing of minimal substrates by ADAR1The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling proteinEvolutionarily conserved human targets of adenosine to inosine RNA editingAntisense-mediated inhibition of human immunodeficiency virus (HIV) replication by use of an HIV type 1-based vector results in severely attenuated mutants incapable of developing resistanceModulation of microRNA processing and expression through RNA editing by ADAR deaminasesADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cellsEditor meets silencer: crosstalk between RNA editing and RNA interferencePrognostic significance of copy-number alterations in multiple myelomaA Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminaseHuman RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducibleA role for Z-DNA binding in vaccinia virus pathogenesisWidespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptomeIdentification of RNA editing sites in the SNP databaseModulation of ADAR1 editing activity by Z-RNA in vitro.A role for dual viral hits in causation of subacute sclerosing panencephalitisA-to-I editing of coding and non-coding RNAs by ADARsADAR1, inosine and the immune sensing system: distinguishing self from non-selfTo edit or not to edit: regulation of ADAR editing specificity and efficiencyNew Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsAdenosine-to-inosine RNA editing and human diseaseThe ADAR protein familyProtein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responseHost genetic variability and West Nile virus susceptibility.Alpha/Beta Interferon Inhibits Cap-Dependent Translation of Viral but Not Cellular mRNA by a PKR-Independent MechanismStructural and functional insights into human Tudor-SN, a key component linking RNA interference and editingA bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1
P2860
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P2860
Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Expression and regulation by i ...... for two forms of the deaminase
@ast
Expression and regulation by i ...... for two forms of the deaminase
@en
Expression and regulation by i ...... for two forms of the deaminase
@en-gb
Expression and regulation by i ...... for two forms of the deaminase
@nl
type
label
Expression and regulation by i ...... for two forms of the deaminase
@ast
Expression and regulation by i ...... for two forms of the deaminase
@en
Expression and regulation by i ...... for two forms of the deaminase
@en-gb
Expression and regulation by i ...... for two forms of the deaminase
@nl
prefLabel
Expression and regulation by i ...... for two forms of the deaminase
@ast
Expression and regulation by i ...... for two forms of the deaminase
@en
Expression and regulation by i ...... for two forms of the deaminase
@en-gb
Expression and regulation by i ...... for two forms of the deaminase
@nl
P2860
P3181
P356
P1476
Expression and regulation by i ...... for two forms of the deaminase
@en
P2093
C E Samuel
J B Patterson
P2860
P304
P3181
P356
10.1128/MCB.15.10.5376
P407
P577
1995-10-01T00:00:00Z