Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
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Novel GATA6 mutations in patients with pancreatic agenesis and congenital heart malformationsHepatocyte nuclear factor-1 beta mutations cause neonatal diabetes and intrauterine growth retardation: support for a critical role of HNF-1? in human pancreatic developmentBridge-1, a novel PDZ-domain coactivator of E2A-mediated regulation of insulin gene transcriptionMafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin geneOrganisation of the human PAX4 gene and its exclusion as a candidate for the Wolcott-Rallison syndromeConserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitusImpaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDMMissense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetesIdentification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activityIncreased islet apoptosis in Pdx1+/- miceMechanisms of action of glucagon-like peptide 1 in the pancreasInsulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans.Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyInfantile onset diabetes mellitus in developing countries - IndiaPancreatic Cancer GeneticsEpidemiology and Inherited Predisposition for Sporadic Pancreatic AdenocarcinomaRegenerative medicine in diabetesMolecular mechanisms that differentiate apoptosis from programmed necrosisNew opportunities: harnessing induced pluripotency for discovery in diabetes and metabolismNeonatal diabetes: an expanding list of genes allows for improved diagnosis and treatmentControl of cell identity in pancreas development and regenerationPathogenesis of the metabolic syndrome: insights from monogenic disordersThe thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretionThe Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cellsDevelopment of diabetes mellitus in aging transgenic mice following suppression of pancreatic homeoprotein IDX-1Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A genepdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasisPcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in miceMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsEffects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistancePdx1 level defines pancreatic gene expression pattern and cell lineage differentiationPDX:PBX complexes are required for normal proliferation of pancreatic cells during developmentPancreatic homeodomain transcription factor IDX1/IPF1 expressed in developing brain regulates somatostatin gene transcription in embryonic neural cellsRole of intrinsic DNA binding specificity in defining target genes of the mammalian transcription factor PDX1Nkx2.2 regulates beta-cell function in the mature isletThe PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoterDNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complexRB regulates pancreas development by stabilizing Pdx1
P2860
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P2860
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@ast
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en-gb
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@nl
type
label
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@ast
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en-gb
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@nl
prefLabel
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@ast
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en-gb
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@nl
P2093
P2860
P3181
P356
P1433
P1476
Pancreatic agenesis attributab ...... uman IPF1 gene coding sequence
@en
P2093
D A Stoffers
J F Habener
N T Zinkin
V Stanojevic
W L Clarke
P2860
P2888
P304
P3181
P356
10.1038/NG0197-106
P407
P577
1997-01-01T00:00:00Z
P5875
P6179
1009101743