Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor
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Structural interactions of fibroblast growth factor receptor with its ligandsDevelopment of a highly-potent anti-angiogenic VEGF8-109 heterodimer by directed blocking of its VEGFR-2 binding siteEndorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonismThe cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factorHuman vascular endothelial growth factor B: characterization of recombinant isoforms and generation of neutralizing monoclonal antibodiesEndorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cellsCell signaling by receptor tyrosine kinasesStructural basis of receptor sharing by interleukin 17 cytokinesVascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cellsThe cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysisVascular endothelial growth factor-B in physiology and diseaseStructure of the active core of human stem cell factor and analysis of binding to its receptor KitCrystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activationThe crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolutionLigand recognition and homophilic interactions in Tyro3: structural insights into the Axl/Tyro3 receptor tyrosine kinase familyStructural basis for stem cell factor–KIT signaling and activation of class III receptor tyrosine kinasesStructural basis for ligand and heparin binding to neuropilin B domainsA mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonistStructural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF bindingVariants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding siteDirect contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signalingStructural determinants of growth factor binding and specificity by VEGF receptor 2Structural Insights into the Binding of Vascular Endothelial Growth Factor-B by VEGFR-1D2: RECOGNITION AND SPECIFICITYTotal Chemical Synthesis of Biologically Active Vascular Endothelial Growth FactorMultipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallographyStructural and mechanistic insights into VEGF receptor 3 ligand binding and activationStructure of a heparin-linked biologically active dimer of fibroblast growth factorIsolation of recombinant BMP receptor IA ectodomain and its 2:1 complex with BMP-2Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stabilityMolecular mapping and functional characterization of the VEGF164 heparin-binding domainLong-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularizationMiniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic responseOverview of protein structural and functional folds.Systems biology of vascular endothelial growth factorsVascular endothelial growth factor as an anti-angiogenic target for cancer therapyDimerization of VEGF receptors and implications for signal transduction: a computational study.Vascular endothelial growth factor (VEGF) receptor II-derived peptides inhibit VEGF.Efficient phage display of polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein.Single-chain vascular endothelial growth factor variant with antagonist activity.
P2860
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P2860
Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@ast
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en-gb
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@nl
type
label
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@ast
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en-gb
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@nl
prefLabel
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@ast
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en-gb
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@nl
P2093
P3181
P1433
P1476
Crystal structure at 1.7 A res ...... domain 2 of the Flt-1 receptor
@en
P2093
A M de Vos
C Eigenbrot
C Wiesmann
H W Christinger
P304
P3181
P356
10.1016/S0092-8674(00)80456-0
P407
P577
1997-11-28T00:00:00Z