The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins
about
Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formationAMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptorCubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epitheliaCubilin is an albumin binding protein important for renal tubular albumin reabsorptionCrystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolutionFrom bowel to kidneys: the role of cubilin in physiology and diseaseUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsA two-receptor pathway for catabolism of Clara cell secretory protein in the kidneyMegalin acts in concert with cubilin to mediate endocytosis of high density lipoproteinsCubilin, a binding partner for galectin-3 in the murine utero-placental complexLoss of albumin and megalin binding to renal cubilin in rats results in albuminuria after total body irradiationDab2, megalin, cubilin and amnionless receptor complex might mediate intestinal endocytosis in the suckling ratCubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomyThe endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptakeUptake of lipoproteins for axonal growth of sympathetic neuronsIdentification and characterization of two distinct ligand binding regions of cubilinLoss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubulesCubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosisGenetic disorders of vitamin B12 metabolism: eight complementation groups – eight genesAssociation Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.CUBN is a gene locus for albuminuria.A CUB-serine protease in the olfactory organ of the spiny lobster Panulirus argus.HDL-holoparticle uptake by alveolar type II cells: effect of vitamin E status.Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complexMegalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.The intrinsic factor-vitamin B12 receptor, cubilin, is assembled into trimers via a coiled-coil alpha-helix.The effect of progressive glomerular disease on megalin-mediated endocytosis in the kidneyUnraveling the mysteries of serum albumin-more than just a serum protein.Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule.The ABCs of membrane transporters in health and disease (SLC series): introduction.Cubilin is essential for albumin reabsorption in the renal proximal tubule.The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins.Proximal tubule endocytic apparatus as the specific renal uptake mechanism for vitamin D-binding protein/25-(OH)D3 complex.MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.Vitamin E as an antioxidant of the lung: mechanisms of vitamin E delivery to alveolar type II cells.Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.Juvenile selective vitamin B₁₂ malabsorption: 50 years after its description-10 years of genetic testing
P2860
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P2860
The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The intrinsic factor-vitamin B ...... logy to developmental proteins
@ast
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en-gb
The intrinsic factor-vitamin B ...... logy to developmental proteins
@nl
type
label
The intrinsic factor-vitamin B ...... logy to developmental proteins
@ast
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en-gb
The intrinsic factor-vitamin B ...... logy to developmental proteins
@nl
prefLabel
The intrinsic factor-vitamin B ...... logy to developmental proteins
@ast
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en-gb
The intrinsic factor-vitamin B ...... logy to developmental proteins
@nl
P2093
P921
P356
P1476
The intrinsic factor-vitamin B ...... logy to developmental proteins
@en
P2093
E I Christensen
F Pontillon
H H Rasmussen
J H Kaysen
M Kristiansen
P J Verroust
S K Moestrup
T G Hammond
P304
P356
10.1074/JBC.273.9.5235
P407
P577
1998-02-27T00:00:00Z