Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery
about
Structures of human Golgi-resident glutaminyl cyclase and its complexes with inhibitors reveal a large loop movement upon inhibitor bindingStructural and functional analyses of a glutaminyl cyclase from Ixodes scapularis reveal metal-independent catalysis and inhibitor bindingIdentification of Glutaminyl Cyclase Genes Involved in Pyroglutamate Modification of Fungal Lignocellulolytic EnzymesLinked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivoStructural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous TrifluoroethanolMapping the zinc-transporting system in mammary cells: molecular analysis reveals a phenotype-dependent zinc-transporting network during lactationGlutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug developmentGlutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegenerationPYROGLUTAMATE FORMATION AT THE N-TERMINI OF ABRI MOLECULES IN FAMILIAL BRITISH DEMENTIA IS NOT RESTRICTED TO THE CENTRAL NERVOUS SYSTEM.Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer diseaseThe isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.Glutaminyl cyclases as novel targets for the treatment of septic arthritis.A single transcription factor is sufficient to induce and maintain secretory cell architectureN-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity.Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.Structural analysis of the pyroglutamate-modified isoform of the Alzheimer's disease-related amyloid-β using NMR spectroscopy.Common variants in QPCT gene confer risk of schizophrenia in the Han Chinese population.
P2860
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P2860
Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Isolation of an isoenzyme of h ...... e protein maturation machinery
@ast
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en-gb
Isolation of an isoenzyme of h ...... e protein maturation machinery
@nl
type
label
Isolation of an isoenzyme of h ...... e protein maturation machinery
@ast
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en-gb
Isolation of an isoenzyme of h ...... e protein maturation machinery
@nl
prefLabel
Isolation of an isoenzyme of h ...... e protein maturation machinery
@ast
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en-gb
Isolation of an isoenzyme of h ...... e protein maturation machinery
@nl
P2093
P50
P921
P1476
Isolation of an isoenzyme of h ...... e protein maturation machinery
@en
P2093
Anett Stephan
Astrid Kehlen
Birgit Koch
Michael Wermann
Stephan Schilling
P304
P356
10.1016/J.JMB.2008.03.078
P407
P577
2008-06-20T00:00:00Z