The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
about
SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.Structure and apoptotic function of p73The p53 circuit boardN4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodiesEhrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection.SIMPLE/LITAF expression induces the translocation of the ubiquitin ligase itch towards the lysosomal compartments.Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2.Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neuronsGenistein suppresses prostate cancer growth through inhibition of oncogenic microRNA-151.The ubiquitin E3 ligase ITCH enhances breast tumor progression by inhibiting the Hippo tumor suppressor pathway.Regulation of p73 activity by post-translational modifications.p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase ItchMicroRNA 16 modulates epithelial sodium channel in human alveolar epithelial cellsIsoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms.Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunityNo exit: targeting the budding process to inhibit filovirus replication.How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors.Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities.A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression.Multifaceted role of the ubiquitin ligase Itch in immune regulation.Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.The E3 ligase Itch in immune regulation and beyond.p73-Binding Partners and Their Functional Significance.RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagyZC3H12A/MCPIP1/Regnase-1-related endonucleases: An evolutionary perspective on molecular mechanisms and biological functions.Herpes simplex virus UL56 interacts with and regulates the Nedd4-family ubiquitin ligase Itch.UbiNet: an online resource for exploring the functional associations and regulatory networks of protein ubiquitylation.A regulatory circuit controlling Itch-mediated p73 degradation by Runx.The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration.The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation.C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation.Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing.
P2860
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P248
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P2860
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@ast
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en-gb
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@nl
type
label
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@ast
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en-gb
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@nl
prefLabel
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@ast
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en-gb
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
@en
P2093
Andrew Oberst
Gerry Melino
Martina Malatesta
Moshe Oren
Paolo Salomoni
Prashant Sharma
Rami I Aqeilan
P2860
P304
P3181
P356
10.1073/PNAS.0701773104
P407
P577
2007-07-03T00:00:00Z