Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis
about
Mnk kinase pathway: Cellular functions and biological outcomesp38α mitogen-activated protein kinase depletion and repression of signal transduction to translation machinery by miR-124 and -128 in neuronsRegulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responsesIFN-γ-mediated hematopoietic cell destruction in murine models of immune-mediated bone marrow failure.Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization.Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responsesInhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors.The oncogene eIF4E: using biochemical insights to target cancer.Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursorsTargeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition.The schlafen family of proteins and their regulation by interferons.Regulation of interferon-dependent mRNA translation of target genesInterferon receptor signaling in malignancy: a network of cellular pathways defining biological outcomes.Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells.The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding.Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.The Regulatory Role of IFN-γ on the Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.Regulatory effects of programmed cell death 4 (PDCD4) protein in interferon (IFN)-stimulated gene expression and generation of type I IFN responses.Mnk1 is a novel acinar cell-specific kinase required for exocrine pancreatic secretion and response to pancreatitis in mice.
P2860
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P2860
Essential role for Mnk kinases in type II interferon (IFNgamma) signaling and its suppressive effects on normal hematopoiesis
description
2011 nî lūn-bûn
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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@ast
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en-gb
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@nl
type
label
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@ast
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en-gb
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@nl
prefLabel
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@ast
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en-gb
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@nl
P2093
P2860
P921
P3181
P356
P1476
Essential role for Mnk kinases ...... ffects on normal hematopoiesis
@en
P2093
Amit K Verma
Beata Majchrzak
Bhumika Sharma
Leonidas C Platanias
Rikiro Fukunaga
Sonali Joshi
Surinder Kaur
Takeshi Ueda
P2860
P304
P3181
P356
10.1074/JBC.M110.197921
P407
P577
2011-02-25T00:00:00Z