Identification of PP2A complexes and pathways involved in cell transformation - Test2 - elhamkhani - TriplyDB

Identification of PP2A complexes and pathways involved in cell transformation

Identification of PP2A complexes and pathways involved in cell transformation

http://www.wikidata.org/entity/Q24316472

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The broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia The biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificity Circumventing embryonic lethality with Lcmt1 deficiency: generation of hypomorphic Lcmt1 mice with reduced protein phosphatase 2A methyltransferase expression and defects in insulin signaling Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway TBC1D3, a hominoid-specific gene, delays IRS-1 degradation and promotes insulin signaling by modulating p70 S6 kinase activity A High-Efficiency Cellular Extraction System for Biological Proteomics Identification and functional analysis of variant haplotypes in the 5'-flanking region of protein phosphatase 2A-Bδ gene.Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer.Phorbol esters in seed oil of Jatropha curcas L. (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics.PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasis Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.Role of a novel functional variant in the PPP2R1A promoter on the regulation of PP2A-Aalpha and the risk of hepatocellular carcinoma The tumor suppressor CDKN3 controls mitosis.Co-modulated behavior and effects of differentially expressed miRNA in colorectal cancer.Viewing serine/threonine protein phosphatases through the eyes of drug designers Phosphatases: the new brakes for cancer development?PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells Restricted protein phosphatase 2A targeting by Merkel cell polyomavirus small T antigen.Retroviral cyclin enhances cyclin-dependent kinase-8 activity.Peroxisome proliferator-activated receptor γ decouples fatty acid uptake from lipid inhibition of insulin signaling in skeletal muscle Signalling by protein phosphatases and drug development: a systems-centred view.Circumventing cellular control of PP2A by methylation promotes transformation in an Akt-dependent manner Deletion of Pr130 Interrupts Cardiac Development in Zebrafish Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling.Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis.PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells.Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway.DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia.Protein phosphatase 2A: a target for anticancer therapy.Clinical significance of cancerous inhibitor of protein phosphatase 2A in human cancers.OP449 inhibits breast cancer growth without adverse metabolic effects.

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Identification of PP2A complexes and pathways involved in cell transformation

http://www.wikidata.org/entity/Q24316472

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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name

Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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type

label

Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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Identification of PP2A complexes and pathways involved in cell transformation

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0008-5472.CAN-10-2855

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Cancer Research

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Identification of PP2A complexes and pathways involved in cell transformation

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Melissa Hector

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Nathalie Colpaert

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William C Hahn

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P2860

The Hallmarks of Cancer

Molecular cloning and mapping of the brain-abundant B1gamma subunit of protein phosphatase 2A, PPP2R2C, to human chromosome 4p16

PR72, a novel regulator of Wnt signaling required for Naked cuticle function

Overexpression of the cis/trans isomerase PTPA triggers caspase 3-dependent apoptosis

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40

The tumor suppressor PP2A Abeta regulates the RalA GTPase

PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle

Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation

PME-1 protects extracellular signal-regulated kinase pathway activity from protein phosphatase 2A-mediated inactivation in human malignant glioma

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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10474-10484

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24

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2010-12-01T00:00:00Z

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3056544

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