SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease
about
Mutation in the gene encoding ubiquitin ligase LRSAM1 in patients with Charcot-Marie-Tooth diseaseRING finger protein RNF207, a novel regulator of cardiac excitationLoss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth diseaseIdentification of human gene products containing Pro-Pro-x-Tyr (PY) motifs that enhance glutathione and endocytotic marker uptake in yeastSCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.Charcot-Marie-Tooth disease and intracellular trafficSIMPLE mutation analysis in dominant demyelinating Charcot-Marie-Tooth disease: three novel mutationsThe Charcot Marie Tooth disease protein LITAF is a zinc-binding monotopic membrane protein.Membrane fission reactions of the mammalian ESCRT pathway.A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritanceSIMPLE/LITAF expression induces the translocation of the ubiquitin ligase itch towards the lysosomal compartments.The LSD1-interacting protein GILP is a LITAF domain protein that negatively regulates hypersensitive cell death in Arabidopsis.Accumulation of endogenous LITAF in aggresomesLITAF mutations associated with Charcot-Marie-Tooth disease 1C show mislocalization from the late endosome/lysosome to the mitochondria.Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways.Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy.Dysregulated Inflammatory Signaling upon Charcot-Marie-Tooth Type 1C Mutation of SIMPLE Protein.The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C.Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal traffickingPolarization and myelination in myelinating glia.Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth.SIMPLE: A new regulator of endosomal trafficking and signaling in health and diseaseMutation of SIMPLE in Charcot-Marie-Tooth 1C alters production of exosomes.ESCRT & Co.A novel missense mutation of CMT2P alters transcription machinery.Cellular LITAF interacts with frog virus 3 75L protein and alters its subcellular localization.GISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation.LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: implications for Charcot-Marie-Tooth disease.GILP family: a stress-responsive group of plant proteins containing a LITAF motif.Phenotypic spectrum of Charcot-Marie-Tooth disease due to LITAF/SIMPLE mutations: a study of 18 patients.SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
P2860
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P2860
SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@ast
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en-gb
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@nl
type
label
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@ast
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en-gb
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@nl
prefLabel
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@ast
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en-gb
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@nl
P2093
P3181
P356
P1476
SIMPLE interacts with NEDD4 an ...... or Charcot-Marie-Tooth disease
@en
P2093
Andrew J Shirk
Craig L Bennett
Phillip F Chance
Sayed H Hashemi
Susan K Anderson
P3181
P356
10.1002/JNR.20628
P407
P577
2005-10-01T00:00:00Z