Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.
about
Phosphorylation of microtubule-associated protein tau by AMPK-related kinasesMARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK/PAR-1MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomesPAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeletonRegulation of Microtubule Dynamics in Axon Regeneration: Insights from C. elegansTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetEmerging modes of PINK1 signaling: another task for MARK2Tau and tauopathiesHelicobacter pylori usurps cell polarity to turn the cell surface into a replicative nicheJNK pathway activation is controlled by Tao/TAOK3 to modulate ethanol sensitivityPar-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador associationPACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instabilityThe mouse kinome: discovery and comparative genomics of all mouse protein kinasesThe LKB1-AMPK pathway: metabolism and growth control in tumour suppressionThe PAR proteins: fundamental players in animal cell polarization.Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarityStructure and regulation of MARK, a kinase involved in abnormal phosphorylation of Tau protein.Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosisTau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.Microtubule affinity regulating kinase activity in living neurons was examined by a genetically encoded fluorescence resonance energy transfer/fluorescence lifetime imaging-based biosensor: inhibitors with therapeutic potential.TRESK background K(+) channel is inhibited by PAR-1/MARK microtubule affinity-regulating kinases in Xenopus oocytesLoss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeletonCognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged ratsDrosophila models of neurodegenerative diseases.Drosophila tao controls mushroom body development and ethanol-stimulated behavior through par-1.RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.Protein kinase A rescues microtubule affinity-regulating kinase 2-induced microtubule instability and neurite disruption by phosphorylating serine 409.Polarized activities of AMPK and BRSK in primary hippocampal neurons.The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivoKin2, the Budding Yeast Ortholog of Animal MARK/PAR-1 Kinases, Localizes to the Sites of Polarized Growth and May Regulate Septin Organization and the Cell WallMammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton.Extending from PARs in Caenorhabditis elegans to homologues in Haemonchus contortus and other parasitic nematodes.Derepression of pathological cardiac genes by members of the CaM kinase superfamily.Luteinizing hormone receptor activation in ovarian granulosa cells promotes protein kinase A-dependent dephosphorylation of microtubule-associated protein 2D.Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking.
P2860
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P2860
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Protein kinase MARK/PAR-1 is r ...... blishment of neuronal polarity
@nl
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@ast
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en-gb
type
label
Protein kinase MARK/PAR-1 is r ...... blishment of neuronal polarity
@nl
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@ast
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en-gb
prefLabel
Protein kinase MARK/PAR-1 is r ...... blishment of neuronal polarity
@nl
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@ast
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en-gb
P2093
P2860
P921
P3181
P356
P1476
Protein kinase MARK/PAR-1 is r ...... lishment of neuronal polarity.
@en
P2093
Jacek Biernat
Laurent Meijer
Qingyi Zheng-Fischhöfer
Thomas Timm
Yong-Zhong Wu
P2860
P304
P3181
P356
10.1091/MBC.02-03-0046
P407
P577
2002-11-01T00:00:00Z