DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
about
Nucleic Acid sensors and type I interferon production in systemic lupus erythematosusRecognition of damage-associated molecular patterns related to nucleic acids during inflammation and vaccinationSingle nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotidesOverview of the biology of type I interferonsPathogen recognition and activation of the innate immune response in zebrafishProduction of extracellular traps against Aspergillus fumigatus in vitro and in infected lung tissue is dependent on invading neutrophils and influenced by hydrophobin RodAThe RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosisAPOBEC3 proteins mediate the clearance of foreign DNA from human cellsIFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomesIRF7: activation, regulation, modification and functionHMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGEOptineurin negatively regulates the induction of IFNbeta in response to RNA virus infectionIFI16 is an innate immune sensor for intracellular DNAHerpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Emerging roles for the non-canonical IKKs in cancerIFIT1 is an antiviral protein that recognizes 5'-triphosphate RNACyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathwayThe A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responsesERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerizationDAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaBViral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activationRIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediateRNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathwayc-Abl tyrosine kinase interacts with MAVS and regulates innate immune responseThe DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replicationAIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASCAn orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasomeThe tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signalingThe DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune responseMapping a dynamic innate immunity protein interaction network regulating type I interferon productionVaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7Cyclic di-GMP sensing via the innate immune signaling protein STINGIFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIVInnate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genomeMany stimuli pull the necrotic trigger, an overviewThe helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cellsInnate immune sensing of DNA virusesSTING is a direct innate immune sensor of cyclic di-GMPInnate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@ast
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en-gb
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@nl
type
label
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@ast
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en-gb
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@nl
prefLabel
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@ast
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en-gb
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@nl
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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
@en
P2093
Akinori Takaoka
Hideo Negishi
Hideyuki Yanai
Kenya Honda
Myoung Kwon Choi
Tadatsugu Taniguchi
Tatsuhiko Kodama
Tatsuma Ban
Yusuke Ohba
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P304
P3181
P356
10.1038/NATURE06013
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2007-07-08T00:00:00Z
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1033292640