Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit
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Cloning and characterization of a third human lysyl hydroxylase isoformCloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramerERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylaseProlyl 4-hydroxylaseA functional candidate screen for coeliac disease genesLoss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null miceIdentification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzymeIdentification of a novel proline-rich peptide-binding domain in prolyl 4-hydroxylaseAn active Catharanthus roseus desacetoxyvindoline-4-hydroxylase-like gene and its transcriptional regulatory profileCharacterization of the human and mouse genes for the alpha subunit of type II prolyl 4-hydroxylase. Identification of a previously unknown alternatively spliced exon and its expression in various tissues.The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.Unity in diversity, a systems approach to regulating plant cell physiology by 2-oxoglutarate-dependent dioxygenasesProlyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegansSevere Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes.Proteomic analysis of circulating monocytes in Chinese premenopausal females with extremely discordant bone mineral density.Prolyl 4 hydroxylase: a critical target in the pathophysiology of diseases.Co-operative intermolecular kinetics of 2-oxoglutarate dependent dioxygenases may be essential for system-level regulation of plant cell physiology.A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase.The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.Domains b' and a' of protein disulfide isomerase fulfill the minimum requirement for function as a subunit of prolyl 4-hydroxylase. The N-terminal domains a and b enhances this function and can be substituted in part by those of ERp57.Characterization of human type X procollagen and its NC-1 domain expressed as recombinant proteins in HEK293 cells.Characterization of the iron- and 2-oxoglutarate-binding sites of human prolyl 4-hydroxylaseCo-expression of the alpha subunit of human prolyl 4-hydroxylase with BiP polypeptide in insect cells leads to the formation of soluble and insoluble complexes. Soluble alpha-subunit-BiP complexes have no prolyl 4-hydroxylase activity.The acidic C-terminal domain of protein disulfide isomerase is not critical for the enzyme subunit function or for the chaperone or disulfide isomerase activities of the polypeptide.Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription factor alpha-like peptides.Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4-hydroxylases containing one of these polypeptides as their beta subunit.Characterization of human type III collagen expressed in a baculovirus system. Production of a protein with a stable triple helix requires coexpression with the two types of recombinant prolyl 4-hydroxylase subunit.The role of protein disulphide isomerase in the microsomal triacylglycerol transfer protein does not reside in its isomerase activity.Assembly of human prolyl 4-hydroxylase and type III collagen in the yeast pichia pastoris: formation of a stable enzyme tetramer requires coexpression with collagen and assembly of a stable collagen requires coexpression with prolyl 4-hydroxylase.Prolyl 4-hydroxylase isoenzymes I and II have different expression patterns in several human tissues.Egg shell collagen formation in Caenorhabditis elegans involves a novel prolyl 4-hydroxylase expressed in spermatheca and embryos and possessing many unique properties.Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half.P4HA1 mutations cause a unique congenital disorder of connective tissue involving tendon, bone, muscle and the eye.Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct.Cloning of the alpha subunit of prolyl 4-hydroxylase from Drosophila and expression and characterization of the corresponding enzyme tetramer with some unique properties.Prolyl 4-Hydroxylase 2 Promotes B-cell Lymphoma Progression via Hydroxylation of Carabin.Identification of arginine-700 as the residue that binds the C-5 carboxyl group of 2-oxoglutarate in human lysyl hydroxylase 1.Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms.
P2860
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P2860
Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@ast
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en-gb
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@nl
type
label
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@ast
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en-gb
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@nl
prefLabel
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@ast
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en-gb
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@nl
P2093
P2860
P921
P356
P1476
Cloning, baculovirus expressio ...... sulfide-isomerase/beta subunit
@en
P2093
I A MacNeil
K I Kivirikko
T Helaakoski
T Pihlajaniemi
P2860
P304
P356
10.1073/PNAS.92.10.4427
P407
P577
1995-05-09T00:00:00Z