Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells
about
The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionManipulation of the host protein acetylation network by human immunodeficiency virus type 1Bromodomain proteins in HIV infectionStructures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic ResolutionCrystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylationCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbPhosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytesCaffeine prevents transcription inhibition and P-TEFb/7SK dissociation following UV-induced DNA damage.Transcriptional and posttranscriptional regulation of HIV-1 gene expressionAcute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression.CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell regeneration.Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer.The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit.Polo-like kinase 1 inhibits the activity of positive transcription elongation factor of RNA Pol II b (P-TEFb).Viral-host interactions that control HIV-1 transcriptional elongationTwo-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression.Non-coding RNAs: key regulators of mammalian transcription.Functional Interaction between HEXIM and Hedgehog Signaling during Drosophila Wing Development.PKC phosphorylates HEXIM1 and regulates P-TEFb activity.Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites.P-TEFb- the final frontier.Role of noncoding RNAs in the regulation of P-TEFb availability and enzymatic activityCuring HIV: Pharmacologic approaches to target HIV-1 latency.CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation.Control of HIV latency by epigenetic and non-epigenetic mechanisms.Genomic occupancy of the transcriptional co-activators p300 and CBP.Lost in transcription: molecular mechanisms that control HIV latencyRole of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription.Therapeutics Targeting Protein Acetylation Perturb Latency of Human Viruses.Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.HDAC1/NFκB pathway is involved in curcumin inhibiting of Tat-mediated long terminal repeat transactivation.HIV latency reversing agents act through Tat post translational modifications.
P2860
Q21136168-1637E240-D3B4-4AE6-9E61-05EC1D09B669Q24634280-9522B18E-0471-4F0F-95FD-C7EFB08FE7BBQ26795463-AA068072-C45A-4728-B565-8B455FE88ADFQ26829860-5BEF4AC9-B0F8-4FC8-A92C-0E66BA552BACQ27657784-93D41667-F573-4CAF-BF82-42416B63949DQ27683254-97C8B03D-16C5-431A-8BCB-AF1D440CBBC5Q28240747-0384F074-7C3E-4841-B066-9983BAFF7CFDQ28276848-B182BAC4-F7D2-4785-ABCD-84E42E6B1DD8Q28487524-86008E8C-C8BE-4622-8380-83ACE065A0D3Q33614701-845FF2F4-65FC-4E52-9B96-9AC531F6ED45Q34030804-9A3BD89C-8F0D-4CE1-9767-650ECB808C99Q34044359-5F2880BF-CE78-4014-94A4-717EF84489A3Q34240810-33A3F848-5449-430D-94CA-55855721AF9FQ34248908-093EC599-72B4-44FD-A742-232B3E4911C4Q34544409-CB8D4349-74E3-4175-9785-6727C8AD0A1CQ34973763-8B8FF201-F758-4E03-B49A-A8F1ADCB5006Q35026881-BDBB6FAE-5B47-49FD-B8CC-C02134745935Q35668935-151985ED-D963-4A1C-AC38-F104C1A07243Q35805406-E37E39AF-307D-4E09-A970-F7520D3C7B75Q35881657-F8E2EF37-08BE-42B2-B2DF-756B2581D66DQ36017203-A2999367-9456-4056-A4EA-2D3E600148A7Q36305691-B6CEE89C-692F-4E00-903A-A8FD8ECF3ABFQ36386750-82738109-8EE1-4C32-9759-87CF6CC48380Q37271176-54F43370-E102-4F75-95EA-EA71846C9B58Q37356131-C7167704-79DE-4D57-A930-01439A3F63BDQ37631411-A47A86CD-F5AE-41E5-ACCC-E7255EC39D85Q37645582-0E47551E-6DFD-4B8F-AA7E-3E2897D72472Q37740906-CE57C2C2-3897-40E1-9690-226FD21BDFD5Q37972643-A64D3FE8-42D3-453E-A25C-18A9793A083AQ38058189-F4D66736-804D-4DD6-894A-152FF10FDC00Q38091888-DCFC89D7-0FDE-4678-8C84-6DF7C7758634Q38430337-2CA4CEAB-2E7B-4729-9156-3C48DC0A0840Q38723116-79F6EB47-B490-4EB0-B42A-D082BB1CBAC5Q39173861-BC08830F-6A52-41D4-A9F3-7E468EF6EF91Q41641646-54C26FE4-CF64-4A6A-9C1C-C139BABC7E3BQ46689072-68AC2150-6254-4A47-BCDD-0C4B04B95B18Q54214251-0FFF85A6-8CD9-49D2-9256-5A9F97ACFBF8
P2860
Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@ast
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en-gb
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@nl
type
label
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@ast
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en-gb
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@nl
prefLabel
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@ast
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en-gb
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Acetylation of cyclin T1 regul ...... e and inactive P-TEFb in cells
@en
P2093
Angelika Pedal
Eva Herker
Hye-Sook Kwon
Sebastian Schroeder
Sungyoo Cho
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.99
P407
P577
2009-05-20T00:00:00Z