Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
about
DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancerNBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivoMCC, a new interacting protein for Scrib, is required for cell migration in epithelial cellsEpithelial cell polarity: a major gatekeeper against cancer?Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesisDEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticityEmerging role of cell polarity proteins in breast cancer progression and metastasisEpithelial cell polarity determinant CRB3 in cancer developmentNormal morphogenesis of epithelial tissues and progression of epithelial tumors.Differential expression of PDZ domain-containing proteins in human diseases - challenging topics and novel issuesDuctal barriers in mammary epitheliumPar6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandMechanical cell competition kills cells via induction of lethal p53 levelsDifferentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.MYC is a metastasis gene for non-small-cell lung cancerThe Influenza A Virus Protein NS1 Displays Structural PolymorphismFunctional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical SitesThe Mammalian Blood-Testis Barrier: Its Biology and RegulationAberrant overexpression of the cell polarity module scribble in human cancerThe APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesisAsymmetric cell division of stem and progenitor cells during homeostasis and cancerMaximum entropy reconstructions of dynamic signaling networks from quantitative proteomics dataLoss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancerZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarityLoss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.The interdependence of the Rho GTPases and apicobasal cell polarity.NOS1AP associates with Scribble and regulates dendritic spine development.Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion.Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis.A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancersThe Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis.A role for the TGFbeta-Par6 polarity pathway in breast cancer progressionThe lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy.Tumors as organs: complex tissues that interface with the entire organismp120-catenin is essential for terminal end bud function and mammary morphogenesis.A new tumor suppressor that regulates tissue architecture.Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Scribble at the crossroads.Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium.
P2860
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P248
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P2860
Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Deregulation of scribble promo ...... for cell polarity in carcinoma
@ast
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en-gb
Deregulation of scribble promo ...... for cell polarity in carcinoma
@nl
type
label
Deregulation of scribble promo ...... for cell polarity in carcinoma
@ast
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en-gb
Deregulation of scribble promo ...... for cell polarity in carcinoma
@nl
prefLabel
Deregulation of scribble promo ...... for cell polarity in carcinoma
@ast
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en-gb
Deregulation of scribble promo ...... for cell polarity in carcinoma
@nl
P2093
P2860
P921
P3181
P1433
P1476
Deregulation of scribble promo ...... for cell polarity in carcinoma
@en
P2093
Craig Allred
Kenneth C Bergami
Lixing Zhan
Senthil K Muthuswamy
Zhenyu Xuan
P2860
P304
P3181
P356
10.1016/J.CELL.2008.09.045
P407
P577
2008-11-28T00:00:00Z