Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes
about
GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytesDiscs large (Dlg1) complexes in lymphocyte activationHuman homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cellsLocalization of Kv1.3 channels in the immunological synapse modulates the calcium response to antigen stimulation in T lymphocytesRegulation of the discs large tumor suppressor by a phosphorylation-dependent interaction with the beta-TrCP ubiquitin ligase receptorHuman CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cellsDirect binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like proteinDirect interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cellsCraniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large genePSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2AKv1.3 potassium channels are localized in the immunological synapse formed between cytotoxic and target cellsK+ channels as targets for specific immunomodulationTwo adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinaseYes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50Kif13b Regulates PNS and CNS Myelination through the Dlg1 ScaffoldStructure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ ClusteringSubunit composition of Kv1 channels in human CNSThe LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs largeScaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factorsDlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsDLGH1 is a negative regulator of T-lymphocyte proliferationDiscs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells.Post-synaptic density perturbs insulin-induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain.Protein 4.1-mediated membrane targeting of human discs large in epithelial cells.The distribution and function of alternatively spliced insertions in hDlg.Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control.Human homologue of the Drosophila discs large tumor suppressor protein forms an oligomer in solution. Identification of the self-association site.Acquired thermotolerance and expression of the HSP100/ClpB genes of lima bean.Signaling pathways are focused at specialized regions of the plasma membrane by scaffolding proteins of the MAGUK family.Shear stress regulates the endothelial Kir2.1 ion channel.A functional interaction between CD46 and DLG4: a role for DLG4 in epithelial polarization.The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cellsSelective phosphorylation of the Dlg1AB variant is critical for TCR-induced p38 activation and induction of proinflammatory cytokines in CD8+ T cells.Unzipping ion channels.Drosophila immunity: genes on the third chromosome required for the response to bacterial infection.A model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathwayDendritic and synaptic pathology in experimental autoimmune encephalomyelitis.Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function.Subcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.Modulation of Kv1.3 channels by protein kinase A I in T lymphocytes is mediated by the disc large 1-tyrosine kinase Lck complex.
P2860
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P2860
Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@ast
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en-gb
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@nl
type
label
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@ast
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en-gb
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@nl
prefLabel
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@ast
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en-gb
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@nl
P2093
P2860
P921
P3181
P356
P1476
Human homologue of the Drosoph ...... ssium channel in T lymphocytes
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.272.43.26899
P407
P577
1997-10-24T00:00:00Z