MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
about
Mnk kinase pathway: Cellular functions and biological outcomesLoss of MNK function sensitizes fibroblasts to serum-withdrawal induced apoptosisMNK kinases regulate multiple TLR pathways and innate proinflammatory cytokines in macrophages.Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis.Cadmium malignantly transforms normal human breast epithelial cells into a basal-like phenotypeCombined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development.The role of MNK proteins and eIF4E phosphorylation in breast cancer cell proliferation and survivalCharacterization of MNK1b DNA Aptamers That Inhibit Proliferation in MDA-MB231 Breast Cancer CellsInhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistanceThe biological and therapeutic relevance of mRNA translation in cancer.Targeting Mnks for cancer therapy.The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways.MNK kinases facilitate c-myc IRES activity in rapamycin-treated multiple myeloma cellsMKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition.Beta-arrestin-mediated signaling regulates protein synthesis.Locoregional therapy with α-emitting trastuzumab against peritoneal metastasis of human epidermal growth factor receptor 2-positive gastric cancer in mice.The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity.Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.The Role of the p38-MNK-eIF4E Signaling Axis in TNF Production Downstream of the NOD1 Receptor.MAP Kinase-Interacting Kinase 1 Promotes Proliferation and Invasion of Hepatocellular Carcinoma and Is an Unfavorable Prognostic Biomarker.Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer.
P2860
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P2860
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@ast
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en-gb
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@nl
type
label
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@ast
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en-gb
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@nl
prefLabel
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@ast
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en-gb
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@nl
P2093
P921
P356
P1476
MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines
@en
P2093
Andrew Eschenroeder
Carol A Chrestensen
Hermann Gram
Jacquelyn K Shuman
Mark Worthington
Thomas W Sturgill
P304
P356
10.1074/JBC.M607368200
P407
P577
2007-02-16T00:00:00Z