pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility
about
Relevance of weak flavin binding in human D-amino acid oxidaseEffect of ligand binding on human D-amino acid oxidase: implications for the development of new drugs for schizophrenia treatmentSerine racemase: a key player in apoptosis and necrosisNovel human ᴅ-amino acid oxidase inhibitors stabilize an active-site lid-open conformationTime and space profiling of NMDA receptor co-agonist functionsTSPO targeted dendrimer imaging agent: synthesis, characterization, and cellular internalizationGlutamatergic synaptic dysregulation in schizophrenia: therapeutic implications.N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic miceThe neurobiology of D-amino acid oxidase and its involvement in schizophrenia.The DAOA/G30 locus and affective disorders: haplotype based association study in a polydiagnostic approachDecreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patientsActivity of D-amino acid oxidase is widespread in the human central nervous system.Heterogeneity of D-Serine Distribution in the Human Central Nervous System.Association between the DAOA/G72 gene and bipolar disorder and meta-analyses in bipolar disorder and schizophrenia.D-amino acid oxidase-nanoparticle system: a potential novel approach for cancer enzymatic therapy.Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia.The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex.Adaptive evolution and elucidating the potential inhibitor against schizophrenia to target DAOA (G72) isoforms.D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians.Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.The D-amino acid transport by the invertebrate SLC6 transporters KAAT1 and CAATCH1 from Manduca sexta.Expression of the G72/G30 gene in transgenic mice induces behavioral changes.D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog.Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity levelSynaptic and cellular changes induced by the schizophrenia susceptibility gene G72 are rescued by N-acetylcysteine treatment.The C-terminal region of G72 increases D-amino acid oxidase activity.D-serine and schizophrenia: an update.D-Amino acids in the brain and mutant rodents lacking D-amino-acid oxidase activity.D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.G72 primate-specific gene: a still enigmatic element in psychiatric disorders.Identification of pLG72-Induced Oxidative Stress Using Systemic Approaches.The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain.D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine.Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.Expression of D-Amino Acid Oxidase (DAO/DAAO) and D-Amino Acid Oxidase Activator (DAOA/G72) during Development and Aging in the Human Post-mortem Brain.A combined study of genetic association and brain imaging on the DAOA gene in schizophrenia.Interaction between effects of genes coding for dopamine and glutamate transmission on striatal and parahippocampal function.Controversial Effects of D-Amino Acid Oxidase Activator (DAOA)/G72 on D-Amino Acid Oxidase (DAO) Activity in Human Neuronal, Astrocyte and Kidney Cell Lines: The N-methyl D-aspartate (NMDA) Receptor Hypofunction Point of View.Increased serum G72 protein levels in patients with schizophrenia: a potential candidate biomarker.
P2860
Q24309227-C08A6A44-C010-417E-8D58-0CE0766ED5E8Q24316880-7BF90F50-C51A-43A4-A11E-7431E810169CQ27025560-E586DA38-FBB1-4D02-B396-B640FD93C05FQ27684575-75480444-73C2-4227-B0EF-61C2C90459AAQ28084245-33060482-DEF4-4B62-8F15-DDF2BBECACD0Q28566869-A7EF73EF-4E02-4F36-A2C5-8154D48D0C2BQ30387014-F0B45176-EBF4-43D2-B05B-0E092ED3CB33Q30504497-343B0F61-7040-4280-837E-0C4D2F558A0EQ33611796-50931FAB-F7CC-487F-B8E6-2BBBE140AE12Q33643846-E5BC7784-7BF6-405D-8F13-6D5A70E967AFQ33718794-E58C0EF2-E223-4223-B740-6C5F2241F9EAQ33730910-D438B45E-85C9-4CF6-B6F3-509F0FF65AFFQ33797251-2CFEBE39-262B-47AE-A849-ED9D5A69E4E3Q33857039-F9E4005F-7AFB-471B-9A84-1C1D696612A0Q34577760-D80BF34B-F322-451C-8887-9CB1CFA5025FQ35112156-330FDFE4-F165-409A-8E1C-0D07C33AFB22Q35675159-0D5ABFCA-8029-4A88-A6C2-205D173261B9Q35841574-3623C29F-DAB4-4DD0-BDFA-449E491F7196Q36297843-1F43CB59-E922-42F7-8D7B-AA868AC643B8Q36357444-8D62F8C1-07B2-440A-BB38-8A40E37D15DDQ36594403-02412C01-3EE9-46E5-8BBA-EDF2D6BCD685Q36794532-C232071E-BAFB-40C8-9D52-8A90BF92F14DQ36799037-01AB7C5A-0FEF-4DF3-A889-95253C1A78B9Q36810370-FC37ED53-B0CC-42F6-8BFA-F50EE5D25088Q37349910-4991366E-1C3D-4EA9-A642-DD9DDBA7B418Q37535383-FF2EC958-75B3-4732-AE43-888400DEB099Q38031285-74433C3C-C1A4-4BD0-8900-B4EF3CB127DFQ38034652-E9B8F8A7-9528-469C-9FB9-CCC6D87FE921Q38672905-B4F4F186-E8F6-4B46-A042-4D9F71BA3061Q38717701-A9D70956-7224-4742-BA89-F54330CC1AAAQ38749650-4DA4C0E7-751E-4045-BFF2-4C90C094902CQ38821901-DE3946A7-16FE-479A-9E1A-970B55FE87E5Q39062810-4A6AE289-F9A7-4C2A-A255-451D6C5911FEQ39394930-86DAD882-E323-4A64-9A06-B927AC5E238BQ39613722-D46A978B-CB8A-4AF7-8939-5A4EA7603A9EQ42107408-2B892423-9258-471A-850C-EE43549E46F7Q44328757-DBAFA232-557F-4332-8D6C-9D1412398B88Q44694726-AB464E07-B03E-4FC8-BA11-0F4192476C31Q44996725-42F95A63-B6CC-4679-96B7-771D6A030F45Q46516683-C1A5CFBC-23C2-4293-A20B-C869945E0FEC
P2860
pLG72 modulates intracellular D-serine levels through its interaction with D-amino acid oxidase: effect on schizophrenia susceptibility
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@ast
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en-gb
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@nl
type
label
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@ast
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en-gb
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@nl
prefLabel
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@ast
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en-gb
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
pLG72 modulates intracellular ...... n schizophrenia susceptibility
@en
P2093
Jean-Pierre Mothet
Mariagrazia Bernasconi
Mirella S Pilone
P2860
P304
P3181
P356
10.1074/JBC.M709153200
P407
P577
2008-08-08T00:00:00Z