The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers
about
p53 activation by knockdown technologiesThe FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumorsLoss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinomaAberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2 '-deoxycytidineThe histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activityCoordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of FhitFhit is a physiological target of the protein kinase SrcNitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegansThe hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cellsAssociation of FHIT (fragile histidine triad), a candidate tumour suppressor gene, with the ubiquitin-conjugating enzyme hUBC9Analysis of the tumour suppressor genes, FHIT and WT-1, and the tumour rejection genes, BAGE, GAGE-1/2, HAGE, MAGE-1, and MAGE-3, in benign and malignant neoplasms of the salivary glandsGapped BLAST and PSI-BLAST: a new generation of protein database search programsDesigned FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate bindingThe nitrilase superfamily: classification, structure and functionWWOX: a candidate tumor suppressor gene involved in multiple tumor typesThe tumor spectrum in FHIT-deficient miceSequence conservation at human and mouse orthologous common fragile regions, FRA3B/FHIT and Fra14A2/FhitThree-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteinsInhibition of topoisomerase I prevents chromosome breakage at common fragile sitesHuman microRNA genes are frequently located at fragile sites and genomic regions involved in cancersAdenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substratesA census of human cancer genesHint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferasesFusion of the transcription factor TFE3 gene to a novel gene, PRCC, in t(X;1)(p11;q21)-positive papillary renal cell carcinomasMuir-Torre-like syndrome in Fhit-deficient miceLung cancer. 1: prevention of lung cancerTargeted deletion of Wwox reveals a tumor suppressor functionPlasticity of DNA replication initiation in Epstein-Barr virus episomesCollecting duct carcinoma of the kidney: an immunohistochemical study of 11 casesControl of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae.Mate-Pair Sequencing as a Powerful Clinical Tool for the Characterization of Cancers with a DNA Viral EtiologyCommon fragile sites: genomic hotspots of DNA damage and carcinogenesisSerine, glycine and one-carbon units: cancer metabolism in full circleRole of genetics in the diagnosis and prognosis of Crohn's diseaseHigh-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 Å resolutionCrystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteinsControl of 5',5'-dinucleoside triphosphate catabolism by APH1, a Saccharomyces cerevisiae analog of human FHIT
P2860
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P2860
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@ast
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en-gb
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@nl
type
label
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@ast
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en-gb
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@nl
prefLabel
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@ast
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en-gb
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@nl
P2093
P921
P3181
P1433
P1476
The FHIT gene, spanning the ch ...... mal in digestive tract cancers
@en
P2093
M G Cotticelli
P304
P3181
P356
10.1016/S0092-8674(00)81034-X
P407
P577
1996-02-23T00:00:00Z