Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
about
Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancersDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsDifferential effects of genistein on prostate cancer cells depend on mutational status of the androgen receptorRecent progress on nutraceutical research in prostate cancer.Impact of butyrate on PKM2 and HSP90β expression in human colon tissues of different transformation stages: a comparison of gene and protein dataEpigenetic modifications by dietary phytochemicals: implications for personalized nutritionHistone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors.Impact of soy isoflavones on the epigenome in cancer prevention.Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects.Berberine suppresses androgen receptor signaling in prostate cancer.Histone deacetylase modulators provided by Mother Nature.Disease-proportional proteasomal degradation of missense dystrophinsNatural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers.Perspectives on the role of isoflavones in prostate cancer.D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells.Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention.HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancer.Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer.Food components and contaminants as (anti)androgenic molecules.Soy isoflavones and prostate cancer: a review of molecular mechanisms.Molecular basis for the actions of Hsp90 inhibitors and cancer therapy.Cancer stem cells, microRNAs, and therapeutic strategies including natural products.The epigenetic potentials of dietary polyphenols in prostate cancer management.Downregulation of androgen receptors by NaAsO2 via inhibition of AKT-NF-κB and HSP90 in castration resistant prostate cancer.Impact of Epigenetic Dietary Components on Cancer through Histone Modifications.Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors.New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer.Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer CellsInhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients.Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2.Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges.Bioactive natural products for chemoprevention and treatment of castration-resistant prostate cancer.Anticancer Natural Compounds as Epigenetic Modulators of Gene ExpressionPhase IIa, randomized placebo-controlled trial of single high dose cholecalciferol (vitamin D3) and daily Genistein (G-2535) versus double placebo in men with early stage prostate cancer undergoing prostatectomyHDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model.Design, synthesis, and evaluation of the antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates.Beyond androgen deprivation: ancillary integrative strategies for targeting the androgen receptor addiction of prostate cancer.LncRNA-SARCC suppresses renal cell carcinoma (RCC) progression via altering the androgen receptor(AR)/miRNA-143-3p signals.Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism.
P2860
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P2860
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@ast
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en-gb
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@nl
type
label
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@ast
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en-gb
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@nl
prefLabel
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@ast
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en-gb
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@nl
P2093
P921
P3181
P1476
Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function
@en
P2093
Deepa Pookot
Emily J Noonan
Rajvir Dahiya
Shashwati Basak
P304
P3181
P356
10.1158/1535-7163.MCT-08-0617
P407
P577
2008-10-01T00:00:00Z