Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors
about
Ghrelin's second life: from appetite stimulator to glucose regulatorIdentification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labelingIsolation of Zn2+ as an endogenous agonist of GPR39 from fetal bovine serumObestatin partially affects ghrelin stimulation of food intake and growth hormone secretion in rodentsCirculating obestatin levels in normal subjects and in patients with impaired glucose regulation and type 2 diabetes mellitusDifferential contributions of motilin receptor extracellular domains for peptide and non-peptidyl agonist binding and activityGPR39 is coupled to TMEM16A in intestinal fibroblast-like cellsG protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunctionFNDC3A is required for adhesion between spermatids and Sertoli cellsGhrelin: a new player in the control of gastrointestinal functionsThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors1H NMR structural analysis of human ghrelin and its six truncated analogs.Combination of Selective Immunoassays and Mass Spectrometry to Characterize Preproghrelin-Derived Peptides in Mouse TissuesObestatin induction of early-response gene expression in gastrointestinal and adipose tissues and the mediatory role of G protein-coupled receptor, GPR39Ghrelin in female and male reproduction.Ghrelin and obestatin expression in serous ovarian tumours.Motilin stimulates preadipocyte proliferation and differentiation and adipocyte lipid storage.GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healingGPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampusChemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example.Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus.Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions.Conjugated Linoleic Acid Supplementation under a High-Fat Diet Modulates Stomach Protein Expression and Intestinal Microbiota in Adult MiceEffects of two methods of reconstruction of digestive tract after total gastrectomy on gastrointestinal motility in ratsGhrelin: central and peripheral implications in anorexia nervosaGrowth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.Biological effects of obestatin.Ghrelin, neuropeptide Y, and other feeding-regulatory peptides active in the hippocampus: role in learning and memory.Ghrelin and motilin receptors as drug targets for gastrointestinal disorders.The role of obestatin in roux-en-Y gastric bypass-induced remission of type 2 diabetes mellitus.Fatty acid and mineral receptors as drug targets for gastrointestinal disorders.GPR39 receptors and actions of trace metals on pancreatic beta cell function and glucose homoeostasis.Protein kinase inhibitor β enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.GPR39-1b, the 5-transmembrane isoform of GPR39 interacts with neurotensin receptor NTSR1 and modifies its function.Neuro-psychopharmacological perspective of Orphan receptors of Rhodopsin (class A) family of G protein-coupled receptors.β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced HyperglycemiaRelative gene-silencing efficiencies of small interfering RNAs targeting sense and antisense transcripts from the same genetic locus.The constitutively active orphan G-protein-coupled receptor GPR39 protects from cell death by increasing secretion of pigment epithelium-derived growth factor.Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.Ghrelin and Motilin Control Systems in GI Physiology and Therapeutics.
P2860
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P2860
Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning and characterization o ...... ogue and neurotensin receptors
@ast
Cloning and characterization o ...... ogue and neurotensin receptors
@en
Cloning and characterization o ...... ogue and neurotensin receptors
@en-gb
Cloning and characterization o ...... ogue and neurotensin receptors
@nl
type
label
Cloning and characterization o ...... ogue and neurotensin receptors
@ast
Cloning and characterization o ...... ogue and neurotensin receptors
@en
Cloning and characterization o ...... ogue and neurotensin receptors
@en-gb
Cloning and characterization o ...... ogue and neurotensin receptors
@nl
prefLabel
Cloning and characterization o ...... ogue and neurotensin receptors
@ast
Cloning and characterization o ...... ogue and neurotensin receptors
@en
Cloning and characterization o ...... ogue and neurotensin receptors
@en-gb
Cloning and characterization o ...... ogue and neurotensin receptors
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P2093
P356
P1433
P1476
Cloning and characterization o ...... ogue and neurotensin receptors
@en
P2093
A D Howard
D L Hreniuk
L H Van der Ploeg
O C Palyha
S D Feighner
P304
P356
10.1006/GENO.1997.5069
P407
P577
1997-12-15T00:00:00Z