Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes
about
T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agentsMultimerization of the protein-tyrosine phosphatase (PTP)-like insulin-dependent diabetes mellitus autoantigens IA-2 and IA-2beta with receptor PTPs (RPTPs). Inhibition of RPTPalpha enzymatic activityIA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion.Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopesAlternative splicing factor ASF/SF2 is down regulated in inflamed muscle.Peripheral blood methylation profiling of female Crohn's disease patientsCytoplasmic transport signal is involved in phogrin targeting and localization to secretory granules.Mechanisms of dense core vesicle recapture following "kiss and run" ("cavicapture") exocytosis in insulin-secreting cells.Insulin secretagogues activate the secretory granule receptor-like protein-tyrosine phosphatase IAR.Elucidating human phosphatase-substrate networks.Enterovirus infection can induce immune responses that cross-react with beta-cell autoantigen tyrosine phosphatase IA-2/IAR.Kalirin, a cytosolic protein with spectrin-like and GDP/GTP exchange factor-like domains that interacts with peptidylglycine alpha-amidating monooxygenase, an integral membrane peptide-processing enzyme.Partial chromosome 7 duplication with a phenotype mimicking the HOXA1 spectrum disorder.Antibodies to the protein tyrosine phosphatases IAR and IA-2 are associated with progression to insulin-dependent diabetes (IDDM) in first-degree relatives at-risk for IDDM.
P2860
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P2860
Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Cloning and characterization o ...... in insulin-dependent diabetes
@ast
Cloning and characterization o ...... in insulin-dependent diabetes
@en
Cloning and characterization o ...... in insulin-dependent diabetes
@en-gb
Cloning and characterization o ...... in insulin-dependent diabetes
@nl
type
label
Cloning and characterization o ...... in insulin-dependent diabetes
@ast
Cloning and characterization o ...... in insulin-dependent diabetes
@en
Cloning and characterization o ...... in insulin-dependent diabetes
@en-gb
Cloning and characterization o ...... in insulin-dependent diabetes
@nl
prefLabel
Cloning and characterization o ...... in insulin-dependent diabetes
@ast
Cloning and characterization o ...... in insulin-dependent diabetes
@en
Cloning and characterization o ...... in insulin-dependent diabetes
@en-gb
Cloning and characterization o ...... in insulin-dependent diabetes
@nl
P2093
P2860
P921
P3181
P356
P1476
Cloning and characterization o ...... in insulin-dependent diabetes
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.271.40.24817
P407
P577
1996-10-04T00:00:00Z