Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity - Test2 - elhamkhani - TriplyDB

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.wikidata.org/entity/Q24322837

about

Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances Alanine scanning of a putative receptor binding surface of insulin-like growth factor-I The metabolic and mitogenic properties of basal insulin analogues Targeting the insulin-like growth factor pathway in hepatocellular carcinoma Regulation of cardiac autophagy by insulin-like growth factor 1 Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX The IGF system in thyroid cancer: new concepts.Development of a human breast-cancer derived cell line stably expressing a bioluminescence resonance energy transfer (BRET)-based phosphatidyl inositol-3 phosphate (PIP3) biosensor Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B Human monoclonal antibodies to the insulin-like growth factor 1 receptor inhibit receptor activation and tumor growth in preclinical studies.Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.Autocrine/paracrine role of insulin-related growth factors in neurogenesis: local expression and effects on cell proliferation and differentiation in retina Mechanisms by which IGF-I may promote cancer Insulin receptor variant forms and type 2 diabetes mellitus.Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms.The neglected role of insulin-like growth factors in the maternal circulation regulating fetal growth.Proinsulin in development: New roles for an ancient prohormone.LIP expression is regulated by IGF-1R signaling and participates in suppression of anoikis.The double trouble of metabolic diseases: the diabetes-cancer link.In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells.Defined, serum-free conditions for in vitro culture of primary human T-ALL blasts.Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates.Insulin signaling pathways and cardiac growth.Differences in metabolic and mitogenic signallingof insulin glargine and AspB10 human insulin in rats [corrected].Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.Insulin and insulin-like growth factor signaling increases proliferation and hyperplasia of the ovarian surface epithelium and decreases follicular integrity through upregulation of the PI3-kinase pathway The IGF axis and placental function. a mini review.A twenty-first century cancer epidemic caused by obesity: the involvement of insulin, diabetes, and insulin-like growth factors IGF ligand and receptor regulation of mammary development Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells.Role of IGF-1 in glucose regulation and cardiovascular disease.Dysregulation of the Mammalian Target of Rapamycin and p27Kip1 Promotes Intimal Hyperplasia in Diabetes Mellitus Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells.Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects.Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.Obesity related hyperinsulinaemia and hyperglycaemia and cancer development.Type 2 diabetes and cancer: what is the connection?Insulin-like growth factor receptor type I as a target for cancer therapy.The IGF system.

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P2860

Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity

http://www.wikidata.org/entity/Q24322837

description

1993 nî lūn-bûn

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1993 թուականի Մարտին հրատարակուած գիտական յօդուած

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1993 թվականի մարտին հրատարակված գիտական հոդված

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1993年の論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

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1993年論文

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1993年论文

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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Purified hybrid insulin/insuli ...... ot insulin, with high affinity

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C E Field

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K Siddle

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M A Soos

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P2860

Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

Expression and characterization of a functional human insulin-like growth factor I receptor

Purification of insulin-like growth factor I receptor from human placental membranes

Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

A monoclonal anti-peptide antibody reacting with the insulin receptor beta-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptors

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

Insulin-like growth factors I and II.

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419-26

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scholarly article

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10.1042/BJ2900419

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P407

P478

290 ( Pt 2)

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P577

1993-03-01T00:00:00Z

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14745841

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P698

8452530

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Insulin like growth factor 1

insulin binding

Insulin like growth factor 1 receptor

Insulin receptor

P932

1132290

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