Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
about
ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cellsING2 controls the progression of DNA replication forks to maintain genome stabilityThe inhibitor of growth protein 5 (ING5) depends on INCA1 as a co-factor for its antiproliferative effectsNAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b)A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancersExtension of the replicative life span of human diploid fibroblasts by inhibition of the p33ING1 candidate tumor suppressorKeep-ING balance: tumor suppression by epigenetic regulationING1 and 5-azacytidine act synergistically to block breast cancer cell growthHistone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor SuppressorOpposite role of yeast ING family members in p53-dependent transcriptional activation.Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3.Differential association of products of alternative transcripts of the candidate tumor suppressor ING1 with the mSin3/HDAC1 transcriptional corepressor complexMolecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletionsHuman ING1 proteins differentially regulate histone acetylationThe candidate tumour suppressor p33ING1 cooperates with p53 in cell growth controlFunctional genetic screen for genes involved in senescence: role of Tid1, a homologue of the Drosophila tumor suppressor l(2)tid, in senescence and cell survivalThe p53 tumor suppressor is stabilized by inhibitor of growth 1 (ING1) by blocking polyubiquitinationIsolation of efficient antivirals: genetic suppressor elements against HIV-1.Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.Expression of novel ING variants is regulated by thyroid hormone in the Xenopus laevis tadpole.Genetic synthetic lethality screen at the single gene level in cultured human cells.Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis.Interspecies data mining to predict novel ING-protein interactions in human.A reassessment of the telomere hypothesis of senescence.ING proteins as potential anticancer drug targets.DNA copy number losses in human neoplasms.Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis.The ING gene family in the regulation of cell growth and tumorigenesis.Tumor cell apoptosis mediated by cytoplasmic ING1 is associated with improved survival in oral squamous cell carcinoma patients.UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.Yng2p-dependent NuA4 histone H4 acetylation activity is required for mitotic and meiotic progression.Reduced ING1 levels in breast cancer promotes metastasisAllelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.Phylogenetic analysis of the ING family of PHD finger proteins.The ING1a tumor suppressor regulates endocytosis to induce cellular senescence via the Rb-E2F pathway.Src regulates the activity of the ING1 tumor suppressor.
P2860
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P2860
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@ast
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en-gb
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@nl
type
label
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@ast
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en-gb
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@nl
prefLabel
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@ast
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en-gb
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@nl
P2093
P356
P1433
P1476
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation
@en
P2093
I Garkavtsev
K Riabowol
P2860
P2888
P304
P356
10.1038/NG1296-415
P407
P577
1996-12-01T00:00:00Z
P5875
P6179
1034201592