Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
about
Congenital sensorineural deafness in dalmatian dogs associated with quantitative trait lociIntegrating the biophysical and molecular mechanisms of auditory hair cell mechanotransductionA missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulationReview series: The cell biology of hearingWhere hearing starts: the development of the mammalian cochleaEps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.High-speed depolymerization at actin filament ends jointly catalysed by Twinfilin and Srv2/CAP.Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8An alteration in ELMOD3, an Arl2 GTPase-activating protein, is associated with hearing impairment in humansA Biophysical Model for the Staircase Geometry of StereociliaThe R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J miceFCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice.The physiology of mechanoelectrical transduction channels in hearing.Genetics of auditory mechano-electrical transduction.β-Actin and fascin-2 cooperate to maintain stereocilia length.Actin in hair cells and hearing loss.Functional assembly of mammalian cochlear hair cellsMutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.A corticosteroid-responsive transcription factor, promyelocytic leukemia zinc finger protein, mediates protection of the cochlea from acoustic trauma.Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice.Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia.Progressive hearing loss and gradual deterioration of sensory hair bundles in the ears of mice lacking the actin-binding protein Eps8L2.Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells.Fascin 2b is a component of stereocilia that lengthens actin-based protrusions.Targeting of the hair cell proteins cadherin 23, harmonin, myosin XVa, espin, and prestin in an epithelial cell model.A novel high throughput invasion screen identifies host actin regulators required for efficient cell entry by Toxoplasma gondii.Coupling of the mechanotransduction machinery and F-actin polymerization in the cochlear hair bundlesWhirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II.Correlation of actin crosslinker and capper expression levels with stereocilia growth phases.Actin-depolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics.Hearing molecules, mechanism and transportation: modeled in Drosophila melanogaster.Proteomics studies in inner ear disorders: pathophysiology and biomarkers.Stereocilia morphogenesis and maintenance through regulation of actin stability.MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions.Global Analysis of Protein Expression of Inner Ear Hair Cells.The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.A twinfilin-like protein coordinates karyokinesis by influencing mitotic spindle elongation and DNA replication in Leishmania.Heterodimeric capping protein is required for stereocilia length and width regulation.Molecular mechanism for inhibition of twinfilin by phosphoinositides.
P2860
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P2860
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@ast
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en-gb
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@nl
type
label
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@ast
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en-gb
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@nl
prefLabel
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@ast
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en-gb
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@nl
P2093
P2860
P921
P1476
Twinfilin 2 regulates actin filament lengths in cochlear stereocilia
@en
P2093
Inna A Belyantseva
Stefan Heller
Thomas B Friedman
P2860
P304
15083-15088
P356
10.1523/JNEUROSCI.2782-09.2009
P407
P577
2009-12-01T00:00:00Z