Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription
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Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testisTranscription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA bindingHuman general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcriptionCloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIIDA mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domainsUncleaved TFIIA is a substrate for taspase 1 and active in transcriptionhTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase IIDistinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complexThe coactivator p15 (PC4) initiates transcriptional activation during TFIIA-TFIID-promoter complex formationFunctional dissection of a human Dr1-DRAP1 repressor complexAn interplay between TATA box-binding protein and transcription factors IIE and IIA modulates DNA binding and transcriptionInteraction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complexAnalysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation.Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNAEfficient binding of NC2.TATA-binding protein to DNA in the absence of TATAProteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cellsThe general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoterMolecular genetics of the RNA polymerase II general transcriptional machineryA testis-specific transcription factor IIA (TFIIAtau) stimulates TATA-binding protein-DNA binding and transcription activation.Activity of the upstream TATA-less promoter of the p21(Waf1/Cip1) gene depends on transcription factor IIA (TFIIA) in addition to TFIIA-reactive TBP-like protein.Acetyl coenzyme A stimulates RNA polymerase II transcription and promoter binding by transcription factor IID in the absence of histones.Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity.Expression and purification of recombinant human c-Fos/c-Jun that is highly active in DNA binding and transcriptional activation in vitroStructural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II.Promoter scanning for transcription inhibition with DNA-binding polyamides.Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription.Human mediator enhances activator-facilitated recruitment of RNA polymerase II and promoter recognition by TATA-binding protein (TBP) independently of TBP-associated factors.Taspase1 processing alters TFIIA cofactor properties in the regulation of TFIID.Single-molecule fluorescence resonance energy transfer shows uniformity in TATA binding protein-induced DNA bending and heterogeneity in bending kinetics.Human TFIID binds to core promoter DNA in a reorganized structural state.A class of activation domains interacts directly with TFIIA and stimulates TFIIA-TFIID-promoter complex assembly.Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIAHigh-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex.Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA.Separation of the transcriptional coactivator and antirepression functions of transcription factor IIADistamycin A and tallimustine inhibit TBP binding and basal in vitro transcription.TBP-like protein (TLP) interferes with Taspase1-mediated processing of TFIIA and represses TATA box gene expression.Phosphorylation of TFIIA stimulates TATA binding protein-TATA interaction and contributes to maximal transcription and viability in yeast.A region within the RAP74 subunit of human transcription factor IIF is critical for initiation but dispensable for complex assembly.
P2860
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P2860
Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription
description
1994 nî lūn-bûn
@nan
1994 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@ast
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en-gb
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@nl
type
label
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@ast
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en-gb
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@nl
prefLabel
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@ast
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en-gb
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@nl
P2093
P921
P356
P1433
P1476
Reconstitution of human TFIIA ...... n TFIID-mediated transcription
@en
P2093
P304
P356
10.1101/GAD.8.19.2336
P407
P577
1994-10-01T00:00:00Z