The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
about
Efficient assembly of de novo human artificial chromosomes from large genomic loci.Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts.Specific association of the gene product of PKD2 with the TRPC1 channelThe polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeletonPolycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 proteinA polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesThe human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-terminiHomo- and heterodimeric interactions between the gene products of PKD1 and PKD2Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutationPKD1 interacts with PKD2 through a probable coiled-coil domainCleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.The structure of a PKD domain from polycystin-1: implications for polycystic kidney disease.The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activityLiver and kidney disease in ciliopathiesInteraction between RGS7 and polycystinRenal cystic disease in tuberous sclerosis: role of the polycystic kidney disease 1 geneA spectrum of mutations in the second gene for autosomal dominant polycystic kidney disease (PKD2)Novel and de novo PKD1 mutations identified by multiple restriction fragment-single strand conformation polymorphism (MRF-SSCP)The Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney DiseasePolycystin-1: a master regulator of intersecting cystic pathwaysMicroRNAs in the pathogenesis of cystic kidney diseaseExperimental therapies and ongoing clinical trials to slow down progression of ADPKDPolycystin-1 cleavage and the regulation of transcriptional pathwaysIdentification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models.Structural and molecular basis of the assembly of the TRPP2/PKD1 complexCalcium binding by the PKD1 domain regulates interdomain flexibility inVibrio choleraemetalloprotease PrtVIn vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2Mutations of the human polycystic kidney disease 2 (PKD2) geneA translation frameshift mutation induced by a cytosine insertion in the polycystic kidney disease 2 gene (PDK2)Regulation of calcium signaling by polycystin-2Experimental verification of a predicted intronic microRNA in human NGFR gene with a potential pro-apoptotic functionCardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 geneRegulation of ryanodine receptor-dependent calcium signaling by polycystin-2Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptorsCardiac defects and renal failure in mice with targeted mutations in Pkd2Nek8 regulates the expression and localization of polycystin-1 and polycystin-2HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesisPkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells
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P2860
The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The polycystic kidney disease ...... tiple cell recognition domains
@ast
The polycystic kidney disease ...... tiple cell recognition domains
@en
The polycystic kidney disease ...... tiple cell recognition domains
@en-gb
The polycystic kidney disease ...... tiple cell recognition domains
@nl
type
label
The polycystic kidney disease ...... tiple cell recognition domains
@ast
The polycystic kidney disease ...... tiple cell recognition domains
@en
The polycystic kidney disease ...... tiple cell recognition domains
@en-gb
The polycystic kidney disease ...... tiple cell recognition domains
@nl
prefLabel
The polycystic kidney disease ...... tiple cell recognition domains
@ast
The polycystic kidney disease ...... tiple cell recognition domains
@en
The polycystic kidney disease ...... tiple cell recognition domains
@en-gb
The polycystic kidney disease ...... tiple cell recognition domains
@nl
P2093
P2860
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The polycystic kidney disease ...... tiple cell recognition domains
@en
P2093
Aspinwall R
San Millán JL
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P2888
P304
P3181
P356
10.1038/NG0695-151
P407
P50
P577
1995-06-01T00:00:00Z
P6179
1048967576