Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate
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Structural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes-implications for cyclase catalysis and evolutionSubstrate specificity determinants of class III nucleotidyl cyclasesDetection of secondary binding sites in proteins using fragment screeningDistinct roles of soluble and transmembrane adenylyl cyclases in the regulation of flagellar motility in Ciona sperm.New structural forms of a mycobacterial adenylyl cyclase Rv1625c.Soluble adenylyl cyclase in health and disease.Ae4 (Slc4a9) Anion Exchanger Drives Cl- Uptake-dependent Fluid Secretion by Mouse Submandibular Gland Acinar Cells.The YHS-Domain of an Adenylyl Cyclase from Mycobacterium phlei Is a Probable Copper-Sensor Module.Biphasic role of calcium in mouse sperm capacitation signaling pathwaysBithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator SiteDifferent cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.Soluble adenylyl cyclase is essential for proper lysosomal acidificationCatalytic Mechanism of Mammalian Adenylyl Cyclase: A Computational Investigation.Role of soluble adenylyl cyclase in mitochondria.New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout miceSperm Capacitation and Acrosome Reaction in Mammalian Sperm.Characterization of a novel signal transducer element intrinsic to class IIIa/b adenylate cyclases and guanylate cyclases.Sperm Sensory Signaling.International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases.Regulation by the quorum sensor from Vibrio indicates a receptor function for the membrane anchors of adenylate cyclases.Protein Kinase A Governs Oxidative Phosphorylation Kinetics and Oxidant Emitting Potential at Complex I.Report on the Third Symposium "cCMP and cUMP as New Second Messengers".Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation.Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites.Perspective on Protein Arginine Deiminase Activity-Bicarbonate Is a pH-Independent Regulator of Citrullination.Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications.Functional Significance of the Adcy10-Dependent Intracellular cAMP Compartments.
P2860
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P2860
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate
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2014年の論文
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2014年論文
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2014年论文
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name
Crystal structures of human so ...... activation through bicarbonate
@ast
Crystal structures of human so ...... activation through bicarbonate
@en
Crystal structures of human so ...... activation through bicarbonate
@en-gb
Crystal structures of human so ...... activation through bicarbonate
@nl
type
label
Crystal structures of human so ...... activation through bicarbonate
@ast
Crystal structures of human so ...... activation through bicarbonate
@en
Crystal structures of human so ...... activation through bicarbonate
@en-gb
Crystal structures of human so ...... activation through bicarbonate
@nl
prefLabel
Crystal structures of human so ...... activation through bicarbonate
@ast
Crystal structures of human so ...... activation through bicarbonate
@en
Crystal structures of human so ...... activation through bicarbonate
@en-gb
Crystal structures of human so ...... activation through bicarbonate
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Crystal structures of human so ...... activation through bicarbonate
@en
P2093
Joop van den Heuvel
Sebastien Moniot
Silke Kleinboelting
P2860
P304
P3181
P356
10.1073/PNAS.1322778111
P407
P577
2014-03-11T00:00:00Z