Molecular basis of ligand recognition and transport by glucose transporters
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Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transportersUniporter substrate binding and transport: reformulating mechanistic questionsChemical Approach to Positional Isomers of Glucose-Platinum Conjugates Reveals Specific Cancer Targeting through Glucose-Transporter-Mediated Uptake in Vitro and in VivoMechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amidesMammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical PhospholipidsWZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site.Membrane Phase-Dependent Occlusion of Intramolecular GLUT1 Cavities Demonstrated by Simulations.Avian and Mammalian Facilitative Glucose Transporters.Attacking the supply wagons to starve cancer cells to death.Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation.Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual ScreeningA high-content screening platform with fluorescent chemical probes for the discovery of first-in-class therapeutics.A Novel Fluorescence Resonance Energy Transfer-Based Screen in High-Throughput Format To Identify Inhibitors of Malarial and Human Glucose TransportersMolecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE.Identification of an Extracellular Gate for the Proton-coupled Folate Transporter (PCFT-SLC46A1) by Cysteine Cross-linking.Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.How does the chemical potential of the substrate drive a uniporter?SLC Transporters: Structure, Function, and Drug Discovery.SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.Functional characterization of human equilibrative nucleoside transporter 1.Rate of entropy model for irreversible processes in living systems.GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery.The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?Ferrous iron efflux systems in bacteria.Molecular Tools for Facilitative Carbohydrate Transporters (Gluts).d- Versus l-Glucose Conjugation: Mitochondrial Targeting of a Light-Activated Dual-Mode-of-Action Ruthenium-Based Anticancer Prodrug.Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters.Mechanism of high affinity inhibition of the human urate transporter URAT1Comparative stability of Major Facilitator Superfamily transport proteins.Discovery and characterization of verinurad, a potent and specific inhibitor of URAT1 for the treatment of hyperuricemia and gout.Proton-solute coupling mechanism of the maltose transporter from Saccharomyces cerevisiae.Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma.Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3.Affinity and path of binding xylopyranose unto E. coli xylose permease.Membrane-traversing mechanism of thyroid hormone transport by monocarboxylate transporter 8.Tunable GLUT-Hexose Binding and Transport via Modulation of Hexose C-3 Hydrogen-Bonding Capabilities."Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.Reconciling contradictory findings: Glucose transporter 1 (GLUT1) functions as an oligomer of allosteric, alternating access transporters.
P2860
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P2860
Molecular basis of ligand recognition and transport by glucose transporters
description
2015 nî lūn-bûn
@nan
2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Molecular basis of ligand recognition and transport by glucose transporters
@ast
Molecular basis of ligand recognition and transport by glucose transporters
@en
Molecular basis of ligand recognition and transport by glucose transporters
@en-gb
Molecular basis of ligand recognition and transport by glucose transporters
@nl
type
label
Molecular basis of ligand recognition and transport by glucose transporters
@ast
Molecular basis of ligand recognition and transport by glucose transporters
@en
Molecular basis of ligand recognition and transport by glucose transporters
@en-gb
Molecular basis of ligand recognition and transport by glucose transporters
@nl
prefLabel
Molecular basis of ligand recognition and transport by glucose transporters
@ast
Molecular basis of ligand recognition and transport by glucose transporters
@en
Molecular basis of ligand recognition and transport by glucose transporters
@en-gb
Molecular basis of ligand recognition and transport by glucose transporters
@nl
P2093
P2860
P921
P3181
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P1433
P1476
Molecular basis of ligand recognition and transport by glucose transporters
@en
P2093
Chuangye Yan
Kunio Hirata
Pengcheng Sun
Shilong Fan
Wenlin Ren
P2860
P2888
P304
P3181
P356
10.1038/NATURE14655
P407
P577
2015-10-15T00:00:00Z
P6179
1021609442