Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
about
Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteasesDeletion of PREPL, a gene encoding a putative serine oligopeptidase, in patients with hypotonia-cystinuria syndrome.Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residueCrystal structure of the tricorn protease reveals a protein disassembly lineElectrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding siteSubstrate-dependent competency of the catalytic triad of prolyl oligopeptidaseElectrostatic environment at the active site of prolyl oligopeptidase is highly influential during substrate bindingStructural framework of fructosyl transfer in Bacillus subtilis levansucraseCrystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formationDipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline ResidueCrystal structures of Trypanosoma brucei oligopeptidase B broaden the paradigm of catalytic regulation in prolyl oligopeptidase family enzymesStructure and Mechanism of the Sphingopyxin I Lasso Peptide IsopeptidaseMolecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity.PREPL: a putative novel oligopeptidase propelled into the limelight.Prolyl oligopeptidase is inhibited in relapsing-remitting multiple sclerosis.Structural and mechanistic analysis of two prolyl endopeptidases: role of interdomain dynamics in catalysis and specificity.Substrate recognition properties of oligopeptidase B from Salmonella enterica serovar Typhimurium.Molecular machines for protein degradation.Pharmacogenetics in model systems: defining a common mechanism of action for mood stabilisers.Circulating FGF21 proteolytic processing mediated by fibroblast activation protein.Parasite prolyl oligopeptidases and the challenge of designing chemotherapeuticals for Chagas disease, leishmaniasis and African trypanosomiasisA typhus group-specific protease defies reductive evolution in rickettsiae.Targeted modification of wheat grain protein to reduce the content of celiac causing epitopes.Molecular dynamics simulations of acylpeptide hydrolase bound to chlorpyrifosmethyl oxon and dichlorvos.Comparative biochemical analysis of three bacterial prolyl endopeptidases: implications for coeliac sprue.Mechanism of Action of Prolyl Oligopeptidase (PREP) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of PREP with Proteins?Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans.Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP.Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometryA new side opening on prolyl oligopeptidase revealed by electron microscopy.Localization of the mRNA encoding prolyl endopeptidase in the rat brain and pituitary.Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV.New diterpene isopimara-7,15-dien-19-oic acid and its prolyl endopeptidase inhibitory activity.Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach.
P2860
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P2860
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@ast
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en-gb
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@nl
type
label
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@ast
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en-gb
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@nl
prefLabel
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@ast
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en-gb
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@nl
P2093
P2860
P356
P1433
P1476
Catalysis of serine oligopeptidases is controlled by a gating filter mechanism
@en
P2093
P2860
P304
P356
10.1093/EMBO-REPORTS/KVD048
P407
P577
2000-09-01T00:00:00Z