Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
about
Occupational and genetic risk factors for osteoarthritis: a reviewCis- and trans-acting gene regulation is associated with osteoarthritisPseudoachondroplasia and multiple epiphyseal dysplasia: a 7-year comprehensive analysis of the known disease genes identify novel and recurrent mutations and provides an accurate assessment of their relative contributionMultiple epiphyseal dysplasia mutations in MATN3 cause misfolding of the A-domain and prevent secretion of mutant matrilin-3Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation.Matrilin-3 Role in Cartilage Development and OsteoarthritisMutations in the known genes are not the major cause of MED; distinctive phenotypic entities among patients with no identified mutationsFunctional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritisLarge scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populationsLinkage to nodal osteoarthritis: quantitative and qualitative analyses of data from a whole-genome screen identify trait-dependent susceptibility loci.Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.Genetic influences on hand osteoarthritis in Finnish women--a replication study of candidate genesGenetic, clinical and radiographic signs in knee osteoarthritis susceptibility.Future directions for the management of pain in osteoarthritisEmerging genetic basis of osteochondritis dissecans.Hand radiology characteristics of patients carrying the T(303)M mutation in the gene for matrilin-3.Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist.Hip joint replacement surgery for idiopathic osteoarthritis aggregates in families.MicroRNAs: Important Epigenetic Regulators in OsteoarthritisRecommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium.Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand.Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage ThicknessThe use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology.Genomewide linkage scan of hand osteoarthritis in female twin pairs showing replication of quantitative trait loci on chromosomes 2 and 19Association between genetic variants of DVWA and osteoarthritis of the knee and hip: a comprehensive meta-analysisBiomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study.Complex trait mapping in isolated populations: Are specific statistical methods required?The matrilins--adaptor proteins in the extracellular matrix.The association between DVWA polymorphisms and osteoarthritis susceptibility: a genetic meta-analysis.Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studiesWhat role for public health in genetics and vice versa?Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper.Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family.Genetics in osteoarthritis.Advances in osteoarthritis geneticsWhat epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases.Analysing the role of endogenous matrix molecules in the development of osteoarthritis.Hand osteoarthritis--a heterogeneous disorder.Genetics of disc-related disorders: current findings and lessons from other complex diseases.
P2860
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P2860
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
name
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3
@nl
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@ast
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en-gb
type
label
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3
@nl
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@ast
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en-gb
prefLabel
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3
@nl
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@ast
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en-gb
P2093
P2860
P50
P3181
P356
P1476
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
@en
P2093
Augustine Kong
Ebba Pálsdóttir
Gerdur Stefánsdóttir
Gudbjörg Olafsdóttir
Gudfinna Sveinbjörnsdóttir
Helgi Jónsson
Hjörtur H Jónsson
Ileana Manolescu
Jeffrey R Gulcher
Kári Stefánsson
P2860
P304
P3181
P356
10.1086/375556
P407
P577
2003-05-07T00:00:00Z