CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans - Test2 - elhamkhani - TriplyDB

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

http://www.wikidata.org/entity/Q24534033

about

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity Regulation of physiological rates in Caenorhabditis elegans by a tRNA-modifying enzyme in the mitochondria Biochemical Genetic Pathways that Modulate Aging in Multiple Species Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans Zinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegans Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.Genetic and pharmacological factors that influence reproductive aging in nematodes Exposure to light enhances pre-adult fitness in two dark-dwelling sympatric species of ants Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum.A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans The mitochondrial unfolded protein response and increased longevity: cause, consequence, or correlation?Ageing, neuronal connectivity and brain disorders: an unsolved ripple effect.clk-1, mitochondria, and physiological rates.The homeobox protein CEH-23 mediates prolonged longevity in response to impaired mitochondrial electron transport chain in C. elegans.A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice.CLK-1/Coq7p is a DMQ mono-oxygenase and a new member of the di-iron carboxylate protein family.Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates.The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins Regulation of C. elegans fat uptake and storage by acyl-CoA synthase-3 is dependent on NR5A family nuclear hormone receptor nhr-25.The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans Quinones in long-lived clk-1 mutants of Caenorhabditis elegans.A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants.Genetic loci modulating fitness and life span in Caenorhabditis elegans: categorical trait interval mapping in CL2a x Bergerac-BO recombinant-inbred worms.The genetics of exceptional human longevity.Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans.Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans.

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P2860

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

http://www.wikidata.org/entity/Q24534033

description

1999 nî lūn-bûn

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1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1999 թվականի ապրիլին հրատարակված գիտական հոդված

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年學術文章

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name

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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type

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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The EMBO Journal

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

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Brown GG

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Ewbank JJ

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Felkai S

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Hekimi S

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Labbé JC

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Lemieux J

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P2860

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.

The biologic clock: the mitochondria?

Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7

The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis

DNA transformation

The genetics of caloric restriction in Caenorhabditis elegans

Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing.

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10.1093/EMBOJ/18.7.1783

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7

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13096369

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10202142

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Caenorhabditis elegans

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1171264

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