A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
about
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosomeRNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodiesCharacterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box proteinProteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicingMinor spliceosome components are predominantly localized in the nucleusHuman splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivoMammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteinsPrp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNAEvolutionary conservation of minor U12-type spliceosome between plants and humansU2 snRNP binds intronless histone pre-mRNAs to facilitate U7-snRNP-dependent 3' end formationModulating splicing with small molecular inhibitors of the spliceosomeX-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60Structural model of the p14/SF3b155{middle dot}branch duplex complexCooperative structure of the heterotrimeric pre-mRNA retention and splicing complexMolecular architecture of the Saccharomyces cerevisiae activated spliceosomeThe DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.Interactions of the yeast SF3b splicing factor.Rds3p is required for stable U2 snRNP recruitment to the splicing apparatus.Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway.Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1Splicing of a rare class of introns by the U12-dependent spliceosomeThe significant other: splicing by the minor spliceosomeThe ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5' to the branch site.Disordered proteinaceous machinesSMN in spinal muscular atrophy and snRNP biogenesisIdentification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation.Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation siteImproved identification of enriched peptide RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometrySplicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay.Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K proteinRibonucleoprotein multimers and their functions.Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.SMN-inducing compounds for the treatment of spinal muscular atrophy.Crystal structure of a core spliceosomal protein interface.Branchpoint selection in the splicing of U12-dependent introns in vitroModified nucleotides at the 5' end of human U2 snRNA are required for spliceosomal E-complex formation.New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study.
P2860
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P2860
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
@nl
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@ast
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@en
type
label
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
@nl
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@ast
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@en
prefLabel
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
@nl
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@ast
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.
@en
P2093
P2860
P50
P356
P1433
P1476
A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site
@en
P2093
A M MacMillan
G Neubauer
N F Katopodis
R Lührmann
P2860
P304
P356
10.1093/EMBOJ/20.16.4536
P407
P577
2001-08-01T00:00:00Z