VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha. - Test2 - elhamkhani - TriplyDB

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.

http://www.wikidata.org/entity/Q24537199

about

Deubiquitylating enzymes and disease Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity The ubiquitin-specific protease USP28 is required for MYC stability HIF1α deubiquitination by USP8 is essential for ciliogenesis in normoxia Isoform-specific localization of the deubiquitinase USP33 to the Golgi apparatus The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization The solution structure of the ZnF UBP domain of USP33/VDU1 A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling DUBs, New Members in the Hypoxia Signaling clUb Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity Hypoxia and metabolic properties of hematopoietic stem cells Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Ubp2 regulates Rsp5 ubiquitination activity in vivo and in vitro.The Rsp5 ubiquitin ligase is coupled to and antagonized by the Ubp2 deubiquitinating enzyme.Antidicer RNAse activity of monocyte chemotactic protein-induced protein-1 is critical for inducing angiogenesis Solution structure of the human ubiquitin-specific protease 15 DUSP domain Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration.Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.Targeted genes and interacting proteins of hypoxia inducible factor-1.HERC2-USP20 axis regulates DNA damage checkpoint through Claspin.HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling Ubiquitin-specific proteases are differentially expressed throughout the Schistosoma mansoni life cycle.Cross Talk between Proliferative, Angiogenic, and Cellular Mechanisms Orchestred by HIF-1α in Psoriasis.SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo.GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α K63-linked ubiquitination in kinase activation and cancer.Molecular pathology of eyes with von Hippel-Lindau (VHL) Disease: a review.The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis Ubiquitin protein modification and signal transduction: implications for inflammatory bowel diseases.RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha Deubiquitinating enzymes as novel anticancer targets.Controlling hair follicle signaling pathways through polyubiquitination.Protein partners of deubiquitinating enzymes.

P2860

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P2860

VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.

http://www.wikidata.org/entity/Q24537199

description

2005 nî lūn-bûn

@nan

2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

VHL protein-interacting deubiq ...... ates and stabilizes HIF-1alpha

@nl

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@ast

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@en

type

label

VHL protein-interacting deubiq ...... ates and stabilizes HIF-1alpha

@nl

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@ast

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@en

prefLabel

VHL protein-interacting deubiq ...... ates and stabilizes HIF-1alpha

@nl

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@ast

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@en

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SJ.EMBOR.7400377

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P1476

VHL protein-interacting deubiq ...... tes and stabilizes HIF-1alpha.

@en

P2093

Dakun Wang

http://www.w3.org/2001/XMLSchema#string

Edward M Messing

http://www.w3.org/2001/XMLSchema#string

Guan Wu

http://www.w3.org/2001/XMLSchema#string

Zaibo Li

http://www.w3.org/2001/XMLSchema#string

P2860

Deubiquitinating enzymes: a new class of biological regulators

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation

The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity

Targeting HIF-1 for cancer therapy

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

P304

373-378

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scholarly article

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4912601

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10.1038/SJ.EMBOR.7400377

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4

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6

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7958977

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15776016

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1299287

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